Ovum

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Overview

A human ovum
Sperm cells attempting to fertilize an ovum

An ovum (plural ova) is a haploid female reproductive cell or gamete. The word is derived from Latin, meaning egg or egg cell. Both animals and embryophytes have ova. The term ovule is used for the young ovum of an animal, as well as the plant structure that carries the female gametophyte and egg cell and develops into a seed after fertilization. In some plants, such as algae, it is also called oosphere.

Material contribution to offspring

The egg is the sole provider of such endosymbiotic organelles, including mitochondria within the cytoplasm. These cannot be produced with nuclear DNA alone and must be manufactured from DNA within existing organelles of their type (such as mitochondrial DNA) — this is important in Human mitochondrial genetics and can be used to trace maternal and paternal ancestry, especially as plants contain chloroplasts as well. Sperm are often too small to contribute anything physical except DNA and its own mitochondria gets destroyed by the egg.

Ova production

In higher animals, ova are produced by female gonads (sexual glands) called ovaries and all of them are present at birth in mammals, and mature via oogenesis.

Human and mammal ova

A sperm cell fusing with an ovum

In the viviparous animals (which include humans and all other placental mammals), the ovum is fertilized inside the female body, and the embryo then develops inside the uterus, receiving nutrition directly from the mother. The ovum is the largest cell in the human body, typically visible to the naked eye without the aid of a microscope or other magnification device. The human ovum measures on average, 145 µm in diameter.

Protist and plant ova

In protists, fungi and many plants, such as bryophytes, ferns, and gymnosperms, ova are produced inside archegonia. Since the archegonium is a haploid structure, egg cells are produced via mitosis. The typical bryophyte archegonium consists of a long neck with a wider base containing the egg cell. Upon maturation, the neck opens to allow sperm cells to swim into the archegonium and fertilize the egg. The resulting zygote then gives rise to an embryo, which will grow out of the archegonium as a sporeling (young sporophyte).

In the flowering plants, the female gametophyte, which usually gives rise to the archegonium, has been reduced to just eight cells referred to as the embryo sac inside the ovule. The gametophyte cell closest to the micropyle opening of the embryo sac develops into the egg cell. Upon pollination, a pollen tube delivers sperm into the embryo sac and one sperm nucleus fuses with the egg nucleus. The resulting zygote develops into an embryo inside the ovule. The ovule in turn develops into a seed and in many cases the plant ovary develops into a fruit to facilitate the dispersal of the seeds. Upon germination, the embryo grows into a seedling.

Ova development in oviparous animals

In the oviparous animals (all birds, most fishes, amphibians and reptiles) the ova develop protective layers and pass through the oviduct to the outside of the body. They are fertilized by male sperm either inside the female body (as in birds), or outside (as in many fishes). After fertilization, an embryo develops, nourished by nutrients contained in the egg. It then hatches from the egg, outside the mother's body. See egg (biology) for a discussion of eggs of oviparous animals.

The egg cell's cytoplasm and mitochondria (and chloroplasts in plants) are the sole means of the egg being able to reproduce by mitosis and eventually form a blastocyst after fertilization.

Ovoviviparity

There is an intermediate form, the ovoviviparous animals: the embryo develops within and is nourished by an egg as in the oviparous case, but then it hatches inside the mother's body shortly before birth, or just after the egg leaves the mother's body. Some fish, reptiles and many invertebrates use this technique.

See also

External links

Cost Effectiveness of Ovum

| group5 = Clinical Trials Involving Ovum | list5 = Ongoing Trials on Ovum at Clinical Trials.govTrial results on OvumClinical Trials on Ovum at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Ovum | list6 = US National Guidelines Clearinghouse on OvumNICE Guidance on OvumNHS PRODIGY GuidanceFDA on OvumCDC on Ovum


| group7 = Textbook Information on Ovum | list7 = Books and Textbook Information on Ovum


| group8 = Pharmacology Resources on Ovum | list8 = AND (Dose)}} Dosing of OvumAND (drug interactions)}} Drug interactions with OvumAND (side effects)}} Side effects of OvumAND (Allergy)}} Allergic reactions to OvumAND (overdose)}} Overdose information on OvumAND (carcinogenicity)}} Carcinogenicity information on OvumAND (pregnancy)}} Ovum in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Ovum


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Ovum | list9 = AND (pharmacogenomics)}} Genetics of OvumAND (pharmacogenomics)}} Pharmacogenomics of OvumAND (proteomics)}} Proteomics of Ovum


| group10 = Newstories on Ovum | list10 = Ovum in the newsBe alerted to news on OvumNews trends on Ovum</small>


| group11 = Commentary on Ovum | list11 = Blogs on Ovum

| group12 = Patient Resources on Ovum | list12 = Patient resources on OvumDiscussion groups on OvumPatient Handouts on OvumDirections to Hospitals Treating OvumRisk calculators and risk factors for Ovum


| group13 = Healthcare Provider Resources on Ovum | list13 = Symptoms of OvumCauses & Risk Factors for OvumDiagnostic studies for OvumTreatment of Ovum

| group14 = Continuing Medical Education (CME) Programs on Ovum | list14 = CME Programs on Ovum

| group15 = International Resources on Ovum | list15 = Ovum en EspanolOvum en Francais

| group16 = Business Resources on Ovum | list16 = Ovum in the MarketplacePatents on Ovum

| group17 = Informatics Resources on Ovum | list17 = List of terms related to Ovum


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