Nitrofurantoin: Difference between revisions

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<small>'''''Brand Names:''''' Alfuran, Apo-Nitrofurantoin, Benkfuran, Berkfurin, Ceduran, Chemiofuran, Cistofuran, Cyantin, Cystit, Dantafur, Fua Med, Fuamed, Fur-Ren, Furabid, Furachel, Furadantin, Furadantin Retard, Furadantina MC, Furadantine, Furadantine Mc, Furadantine-Mc, Furadantoin, Furadoin, Furadoine, Furadonin, Furadonine, Furadontin, Furalan, Furaloid, Furan, Furanite, Furantoin, Furantoina, Furatoin, Furedan, Furina, Furobactina, Furophen T, Furophen T-Caps, Gerofuran, It-Uran, Ituran, Ivadantin, Macpac, Macrobid, Macrodantin, Macrodantina, Macrofuran, Macrofurin, N-Toin, Nierofu, Nifurantin, Nitoin, Nitrex, Nitrofan, Nitrofur-C, Nitrofuradantin, Novo-Furantoin, Novofuran, Orafuran, Parfuran, Phenurin, Ro-Antoin, Siraliden, Trantoin, Uerineks, Upiol, Urantoin, Urizept, Uro-Selz, Uro-Tablinen, Urodin, Urofuran, Urofurin, Urolisa, Urolong, USAF EA-2, Uvaleral, Welfurin, Zoofurin. </small>
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{{Nitrofurantoin}}
'''''For patient information, click <u>[[Nitrofurantoin (patient information)|here]]'''''</u>.


{{CMG}}
{{CMG}}; {{AE}} {{MM}}
==Overview==


==Dosing and Administration==
==Category==
''Adults and Children (older than 12 yr of age)''
Urinary anti-infective
*PO 50 to 100 mg 4 times daily with meals for 7 days minimum and for at least 3 days after sterile urine is obtained. Monohydrate microcrystals: 100 mg every 12 h for 7 days.


''Children (older than 1 mo of age)''
==US Brand Names==
*PO 5 to 7 mg/kg/24 h in 4 divided doses with meals and at bedtime for minimum of 7 days and for at least 3 days after sterile urine is obtained.
FURADANTIN<sup>®</sup>


'''Long-Term Suppressive Therapy'''
==FDA Package Insert==


''Adults''
'''  [[Nitrofurantoin description|Description]]'''
*PO 50 to 100 mg at bedtime.
'''| [[Nitrofurantoin clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Nitrofurantoin microbiology|Microbiology]]'''
'''| [[Nitrofurantoin indications and usage|Indications and Usage]]'''
'''| [[Nitrofurantoin contraindications|Contraindications]]'''
'''| [[Nitrofurantoin warnings and precautions|Warnings and Precautions]]'''
'''| [[Nitrofurantoin adverse reactions|Adverse Reactions]]'''
'''| [[Nitrofurantoin overdosage|Overdosage]]'''
'''| [[Nitrofurantoin dosage and administration|Dosage and Administration]]'''
'''| [[Nitrofurantoin how supplied|How Supplied]]'''
'''| [[Nitrofurantoin labels and packages|Labels and Packages]]'''


''Children''
==Mechanism of Action==
*PO 1 mg/kg per 24 h as a single or 2 divided doses.


''General Advice''
==References==
* Administer with food to improve absorption and tolerability.
{{Reflist|2}}
* Shake oral suspension well before measuring dose.
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[[{{PAGENAME}}#FDA Package Insert Resources|FDA Package Insert Resources]]
<br></font size><small>Indications, Contraindications, Side Effects, Drug Interactions, etc.</small><font size="4"><br>
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[http://www.pace-med-apps.com/gfrcalc.htm Calculate Creatine Clearance]
<br></font size><small>On line calculator of your patients Cr Cl by a variety of formulas.</small><font size="4"><br>
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[http://home.earthlink.net/~sensei11/convert.htm Convert pounds to Kilograms]
<br></font size><small>On line calculator of your patients weight in pounds to Kg for dosing estimates.</small><font size="4"><br>
<br> [[{{PAGENAME}}#Publication Resources|Publication Resources]]
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[[{{PAGENAME}}#Trial Resources|Trial Resources]]
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[[{{PAGENAME}}#Media Resources|Media Resources]]
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[[{{PAGENAME}}#Patient Resources|Patient Resources]]
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[[{{PAGENAME}}#International Resources|International Resources]]
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==FDA Package Insert Resources==
[[Category:Antibiotics]]
[[{{PAGENAME}} indications|Indications]]
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[[{{PAGENAME}} contraindications|Contraindications]]
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[[{{PAGENAME}} overdose|Overdose]]
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[[{{PAGENAME}} instructions for administration|Instructions for Administration]]
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[[{{PAGENAME}} how supplied|How Supplied]]
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[[{{PAGENAME}} pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]]
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[http://www.fda.gov/medwatch/SAFETY/2003/03Oct_PI/Macrobid_PI.pdf FDA label]
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[http://google2.fda.gov/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&x=0&y=0&client=FDA&site=FDA&lr=&proxystylesheet=FDA&output=xml_no_dtd&getfields=* FDA on {{PAGENAME}}]
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==Publication Resources==
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
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[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}%20AND%20systematic%5Bsb%5D  Review Articles on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28%28N+Engl+J+Med%5Bta%5D%29+OR+%28Lancet%5Bta%5D%29+OR+%28BMJ%5Bta%5D%29%29 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
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[[WikiDoc state of the art review on {{PAGENAME}}|WikiDoc State of the Art Review]]
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[http://books.google.com/books?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=gp Textbook Information on {{PAGENAME}}]
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==Trial Resources==
[http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28randomized+controlled+trial%5BPublication+Type%5D+OR+%28randomized%5BTitle%2FAbstract%5D+AND+controlled%5BTitle%2FAbstract%5D+AND+trial%5BTitle%2FAbstract%5D%29%29 Trial Results with {{PAGENAME}}]
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==Guidelines & Evidence Based Medicine Resources==
[http://www.guideline.gov/search/searchresults.aspx?Type=3&txtSearch={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&num=20 US National Guidelines Clearinghouse on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cochrane Database Syst Rev[ta])}} Cochrane Collaboration on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cost effectiveness)}} Cost Effectiveness of {{PAGENAME}}]
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==Media Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+ppt&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Powerpoint Slides on {{PAGENAME}}]
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[http://images.google.com/images?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wi Images of {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial&hs=hPo&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+podcasts+OR+MP3&btnG=Search Podcasts & MP3s on {{PAGENAME}}]
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[http://video.google.com/videosearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&um=1&sa=N&tab=fv# Videos on {{PAGENAME}}]
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==Patient Resources==
[[{{PAGENAME}} (patient information)|Patient Information from National Library of Medicine]]
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[http://www.google.com/search?hl=en&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:for_patients&cx=disease_for_patients&sa=N&oi=cooptsr&resnum=0&ct=col3&cd=1  Patient Resources on {{PAGENAME}}]
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[http://groups.google.com/groups/search?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search Discussion Groups on {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla:en-US:official&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:patient_handouts&cx=disease_for_health_professionals&sa=N&oi=coopctx&resnum=0&ct=col1&cd=3 Patient Handouts on {{PAGENAME}}]
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[http://blogsearch.google.com/blogsearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wb Blogs on {{PAGENAME}}]
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[http://news.google.com/news?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wn {{PAGENAME}} in the News]
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[http://finance.google.com/finance?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=te {{PAGENAME}} in the Marketplace]
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==International Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+en+espanol&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a {{PAGENAME}} en Español]
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{{FDA}}
 
[[Category:Drugs]]

Revision as of 16:53, 9 January 2014