Nephritic syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian

Overview

Approximately 25% of patients with acute glomerulonephritis present with nephritic syndrome.[1] Acute glomerulonephritis accounts for 10-15% of glomerular diseases in the USA.[2] The reported incidence rates of glomerulonephritis in adults varies between 0.2 to 2.5/100,000 annually with a male to female ratio reaching 2 to 1.[3] The most common cause of glomerulonephritis worldwide is IgA nephropathy (Berger disease). Approximately 25-30% of patients eventually develop end-stage renal disease (ESRD).[3] The yearly variation of incidence of glomerulonephritis is not validated. While some studies report a decrease in the incidence due to improved healthcare and socioeconomic status, others report an increase in the reported incidence due to increased number of biopsies.[3] Additionally, the true incidence is difficult to predict because the disease might present subclinically.

References

  1. Chang, A (2009). Glomerulonephritis, Membranopoliferative In: Lang F, ed. Encyclopedia of Molecular Mechanisms of Disease. Springer. pp. 711–6. Unknown parameter |coauthors= ignored (help)
  2. Chang, A (2009). Glomerulonephritis, Membranopoliferative In: Lang F, ed. Encyclopedia of Molecular Mechanisms of Disease. Springer. pp. 711–6. Unknown parameter |coauthors= ignored (help)
  3. 3.0 3.1 3.2 McGrogan A, Franssen CF, de Vries CS (2011). "The incidence of primary glomerulonephritis worldwide: a systematic review of the literature". Nephrol Dial Transplant. 26 (2): 414–30. doi:10.1093/ndt/gfq665. PMID 21068142.

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