Necrotizing fasciitis natural history, complications and prognosis: Difference between revisions
mNo edit summary |
|||
Line 10: | Line 10: | ||
==Complications== | ==Complications== | ||
====Type 2 NF and streptococcal toxic shock syndrome==== | |||
*Most of Type 2 NF cases are associated with [[STSS]] which increases the mortality of streptococcal NF alone from <40% to 67% with up to half of patients needing amputation. | |||
*The superantigens cause massive activation of t-cell, cytokine release, tissue damage and toxic shock-like syndrome | |||
==Prognosis== | ==Prognosis== |
Revision as of 22:27, 4 September 2016
Necrotizing fasciitis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Necrotizing fasciitis natural history, complications and prognosis On the Web |
American Roentgen Ray Society Images of Necrotizing fasciitis natural history, complications and prognosis |
FDA on Necrotizing fasciitis natural history, complications and prognosis |
CDC on Necrotizing fasciitis natural history, complications and prognosis |
Necrotizing fasciitis natural history, complications and prognosis in the news |
Blogs on Necrotizing fasciitis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Natural History
Complications
Type 2 NF and streptococcal toxic shock syndrome
- Most of Type 2 NF cases are associated with STSS which increases the mortality of streptococcal NF alone from <40% to 67% with up to half of patients needing amputation.
- The superantigens cause massive activation of t-cell, cytokine release, tissue damage and toxic shock-like syndrome
Prognosis
This disease is one of the fastest-spreading infections known, as it spreads easily across the fascial plane within the subcutaneous tissue. For this reason, it is popularly called the “flesh-eating disease,” and, although rare, it became well-known to the public in the 1990s. Even with today's modern medicine, the prognosis can be bleak, with a mortality rate of approximately 25% and severe disfigurement common in survivors.