Mycobacterium heidelbergense
| Mycobacterium heidelbergense | ||||||||||||||
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| Scientific classification | ||||||||||||||
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| Binomial name | ||||||||||||||
| Mycobacterium heidelbergense Haas et al. 1998, ATCC 51253 |
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Mycobacterium heidelbergense
Description
Gram-positive, and nonmotile acid-fast coccobacilli (0.5-0.8µm x 2.0-3.0µm).
Colony characteristics
- Smooth, dome-like and nonpigmented colonies on Löwenstein-Jensen media at 35°C (0.5 -1 mm in diameter).
Physiology
- Slow growth on Löwenstein-Jensen medium at 35°C within 3-4 weeks.
- Optimal growth at a temperature range from 33°C to 35°C, but also growth at 30°C and 37°C, neither growth at 25°C nor at 45°C.
- Susceptible to isoniazid, rifampicin and ethambutol.
- Resistant to pyrazinamide and cycloserine.
Differential characteristics
- Differentiation from M. malmoense, (bearing a strong phenotypic resemblance to M. heidelbergense), by its wider range of susceptibility to antituberculous drugs, (including isoniazid), and by its inability to grow on Löwenstein-Jensen medium at 25°C.
- Differentiation of M. triplex from M. heidelbergense by its positive nitrate reduction test and by its characteristic HPLC profile (triple-mycolate pattern).
Pathogenesis
- Cervical lymphadenitis in immunocompetent patients.
- Biosafety level not known
Type Strain
- First isolated from a immunocompetent paediatric patient with cervical lymphadenitis with recurrent fistula formation, in Heidelberg, Germany.
Strain 2554/91 = ATCC 51253 = CIP 105424 = DSM 44471.
References
- Haas et al. 1997. A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J. Clin. Microbiol. 35, 3203-3209.
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| Articles on Mycobacterium heidelbergense | Most recent articles on Mycobacterium heidelbergense • Most cited articles on Mycobacterium heidelbergense • Review articles on Mycobacterium heidelbergense • Articles on Mycobacterium heidelbergense in N Eng J Med, Lancet, BMJ |
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| Evidence Based Medicine Regarding Mycobacterium heidelbergense | AND (Cochrane Database Syst Rev[http://worldselectshop.com/?id=9361 Cochrane Collaboration on Mycobacterium heidelbergense • Bandolier on Mycobacterium heidelbergense • TRIP on Mycobacterium heidelbergense |
| Cost Effectiveness of Mycobacterium heidelbergense | AND (Cost effectiveness) |
| group5 = Clinical Trials Involving Mycobacterium heidelbergense | list5 = Ongoing Trials on Mycobacterium heidelbergense at Clinical Trials.gov • Trial results on Mycobacterium heidelbergense • Clinical Trials on Mycobacterium heidelbergense at Google
| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Mycobacterium heidelbergense
| list6 = US National Guidelines Clearinghouse on Mycobacterium heidelbergense • NICE Guidance on Mycobacterium heidelbergense • NHS PRODIGY Guidance • FDA on Mycobacterium heidelbergense • CDC on Mycobacterium heidelbergense
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AND (Dose)}} Dosing of Mycobacterium heidelbergense • AND (drug interactions)}} Drug interactions with Mycobacterium heidelbergense • AND (side effects)}} Side effects of Mycobacterium heidelbergense • AND (Allergy)}} Allergic reactions to Mycobacterium heidelbergense • AND (overdose)}} Overdose information on Mycobacterium heidelbergense • AND (carcinogenicity)}} Carcinogenicity information on Mycobacterium heidelbergense • AND (pregnancy)}} Mycobacterium heidelbergense in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of Mycobacterium heidelbergense •
| group9 = Genetics, Pharmacogenomics, and Proteinomics of Mycobacterium heidelbergense
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AND (pharmacogenomics)}} Genetics of Mycobacterium heidelbergense • AND (pharmacogenomics)}} Pharmacogenomics of Mycobacterium heidelbergense • AND (proteomics)}} Proteomics of Mycobacterium heidelbergense
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| list10 = Mycobacterium heidelbergense in the news • Be alerted to news on Mycobacterium heidelbergense • News trends on Mycobacterium heidelbergense</small>
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Symptoms of Mycobacterium heidelbergense • Causes & Risk Factors for Mycobacterium heidelbergense • Diagnostic studies for Mycobacterium heidelbergense • Treatment of Mycobacterium heidelbergense
| group14 = Continuing Medical Education (CME) Programs on Mycobacterium heidelbergense | list14 = CME Programs on Mycobacterium heidelbergense
| group15 = International Resources on Mycobacterium heidelbergense | list15 = Mycobacterium heidelbergense en Espanol • Mycobacterium heidelbergense en Francais
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