Multiple endocrine neoplasia type 1 natural history, complications and prognosis

Multiple endocrine neoplasia type 1 Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Natural History

The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___. The symptoms of (disease name) typically develop ___ years after exposure to ___. Without treatment, the patient will develop symptoms of ___, which will/ may eventually lead to ___.

Complications

• Complications that can develop as a result of multiple endocrine neoplasia type 1 are as belows.

• Hypoglycemia
• Diabetes
• Watery diarrhea
• Cushing's syndrome
• Infertility
• Impotency

Prognosis

The prognosis of multiple endocrine neoplasia type 1 is good with treatment. Without treatment, multiple endocrine neoplasia type 1 will result in ___. (Disease name) is associated with a 1/5/10 year mortality of __ among patient with ______ (for example high grade lesions). The presence of ___ is associated with a particularly poor prognosis among patients with multiple endocrine neoplasia type 1.