Minimal change disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian

Overview

Symptoms

  • Fatigue
  • Edema: periorbital edema, weight gain[1]
  • Hypertension
  • Red urine[1][2]
  • Symptoms of infections, such as pneumonia[1]
  • Irritability
  • Headache
  • Depression.[2]
  • Symptoms due to complications of nephrotic syndrome:
    • Thromboembolic events
    • Cardiovascular disease
    • Thyroid dysfunction
    • Hypocalcemia
    • Hypovitaminosis D[2]

References

  1. 1.0 1.1 1.2 Waldman M, Crew RJ, Valeri A, Busch J, Stokes B, Markowitz G; et al. (2007). "Adult minimal-change disease: clinical characteristics, treatment, and outcomes". Clin J Am Soc Nephrol. 2 (3): 445–53. doi:10.2215/CJN.03531006. PMID 17699450.
  2. 2.0 2.1 2.2 Saha TC, Singh H (2006). "Minimal change disease: a review". South Med J. 99 (11): 1264–70. PMID 17195422.

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