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==Overview==
==Overview==


Methemoglobinemia presents with very distinct physical presentation.
Patients with [[methemoglobinemia]] usually present with gray or bluish skin discoloraion. Physical examination of patients with  [[methemoglobinemia]] is usually remarkable for [[headache]], [[tachycardia]], [[dyspnea]] and [[ lightheadedness]]


==Physical Examination==
==Physical Examination==


*Methemoglobinemia patients can present with different shades of bluish skin color, depending on the levels of MetHb in the blood. <ref name="pmid19097728">{{cite journal| author=Chung NY, Batra R, Itzkevitch M, Boruchov D, Baldauf M| title=Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report. | journal=J Emerg Med | year= 2010 | volume= 38 | issue= 5 | pages= 601-6 | pmid=19097728 | doi=10.1016/j.jemermed.2008.06.025 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19097728  }} </ref>
Appearance of the Patient
Methemoglobinemia patients can present with different shades of bluish skin color, depending on the levels of MetHb in the blood. <ref name="pmid19097728">{{cite journal| author=Chung NY, Batra R, Itzkevitch M, Boruchov D, Baldauf M| title=Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report. | journal=J Emerg Med | year= 2010 | volume= 38 | issue= 5 | pages= 601-6 | pmid=19097728 | doi=10.1016/j.jemermed.2008.06.025 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19097728 }} </ref>
 
Vital Signs
[[Tachycardia]] with regular pulse
[[Respiratory depression]]
[[Dyspnea]]
[[Cyanosis]] <ref name="pmid29756717">{{cite journal| author=Orlandi M, Amadi MA, Goldaracena PX, Péreza FE| title=[Cyanosis in 14-year-old patient. Methemoglobinemia: case report]. | journal=Arch Argent Pediatr | year= 2018 | volume= 116 | issue= 3 | pages= e429-e432 | pmid=29756717 | doi=10.5546/aap.2018.e429 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29756717  }} </ref>
Blue-colored skin, lips, and nail beds
[[Pallor]]
 
HEENT
[[Lightheadedness]]
[[Headache]]
 
Extremities
Cyanosis
 
Neuromuscular
[[Fatigue]]
[[Lethargy]]
[[Altered mental status]] in higher MetHb levels
[[Coma]
[[Shock]]
[[Seizures]]<ref name="pmid27397059">{{cite journal| author=Cho YS, Chung BY, Park CW, Kim HO| title=Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis. | journal=Pediatr Dermatol | year= 2016 | volume= 33 | issue= 5 | pages= e284-5 | pmid=27397059 | doi=10.1111/pde.12927 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27397059 }} </ref>


*High methemoglobin levels in arterial blood causes the characteristic chocolate-brown color of the blood as compared to normal bright red oxygen-containing arterial blood.<ref name="pmid25116418">{{cite journal| author=D'sa SR, Victor P, Jagannati M, Sudarsan TI, Carey RA, Peter JV| title=Severe methemoglobinemia due to ingestion of toxicants. | journal=Clin Toxicol (Phila) | year= 2014 | volume= 52 | issue= 8 | pages= 897-900 | pmid=25116418 | doi=10.3109/15563650.2014.947377 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25116418  }} </ref>


==References==
==References==

Revision as of 14:50, 15 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.

Overview

Patients with methemoglobinemia usually present with gray or bluish skin discoloraion. Physical examination of patients with methemoglobinemia is usually remarkable for headache, tachycardia, dyspnea and lightheadedness

Physical Examination

Appearance of the Patient Methemoglobinemia patients can present with different shades of bluish skin color, depending on the levels of MetHb in the blood. [1]

Vital Signs Tachycardia with regular pulse Respiratory depression Dyspnea Cyanosis [2] Blue-colored skin, lips, and nail beds Pallor

HEENT Lightheadedness Headache

Extremities Cyanosis

Neuromuscular Fatigue Lethargy Altered mental status in higher MetHb levels [[Coma] Shock Seizures[3]


References

  1. Chung NY, Batra R, Itzkevitch M, Boruchov D, Baldauf M (2010). "Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report". J Emerg Med. 38 (5): 601–6. doi:10.1016/j.jemermed.2008.06.025. PMID 19097728.
  2. Orlandi M, Amadi MA, Goldaracena PX, Péreza FE (2018). "[Cyanosis in 14-year-old patient. Methemoglobinemia: case report]". Arch Argent Pediatr. 116 (3): e429–e432. doi:10.5546/aap.2018.e429. PMID 29756717.
  3. Cho YS, Chung BY, Park CW, Kim HO (2016). "Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis". Pediatr Dermatol. 33 (5): e284–5. doi:10.1111/pde.12927. PMID 27397059.

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