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{{Menopause}}
{{Menopause}}
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==Age==
The average age of menopause is 51 years, and the normal age range for last period ever is somewhere between age 45 to 55. Age 55 to 60 for last period ever is described as a "late menopause". An "early menopause" is defined as last period ever between the age of 40 to 45.


Some women reach menopause at a much younger age than average, especially if they have had [[cancer]] or another serious illness, and have undergone [[chemotherapy]]. This is sometimes referred to as a "chemical menopause".
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''Premature menopause'' (or ''[[premature ovarian failure]]'') is defined as last period ever occurring before the age of 40; it occurs in 1% of women and is not viewed as being due to normal causes. Some known causes of spontaneous premature menopause include [[autoimmune disorder]]s, [[thyroid]] disease, and [[diabetes mellitus]], but often it is [[idiopathic]] or due to unknown causes.  
==Overview==
The [[prevalence]] of [[menopause]] is estimated to be about 50 million cases annually. [[Menopause]] naturally occurs in [[women]] between 49 to 52 of [[age]] the [[average]]. The [[Fatality rate|fatality]] cases were 345 cases per 3191 [[women]] aged between 50-86 years in the [[United States]]. There is no [[racial]] predilection to [[Menopause]], but   African American [[women]] had experienced the largest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with other [[Ethnic group|ethnic groups]].


Premature menopause is diagnosed or confirmed by measuring the levels of [[follicle stimulating hormone]] (FSH) and [[luteinizing hormone]] (LH); the levels of these hormones will be higher if menopause has occurred. Rates of premature menopause have been found to be significantly higher in fraternal and identical [[twins]]; approximately 5% of twins reach menopause before the age of 40. The reasons for this are not completely understood. Transplants of ovarian tissue between identical twins have been successful in restoring fertility.
==Epidemiology and Demographics==
===Prevalence and Incidence===


*The [[prevalence]] of [[menopause]] is estimated to be about 50 million cases worldwide will go into [[menopause]] annually.<ref name="pmid11716989">{{cite journal| author=Massart F, Reginster JY, Brandi ML| title=Genetics of menopause-associated diseases. | journal=Maturitas | year= 2001 | volume= 40 | issue= 2 | pages= 103-16 | pmid=11716989 | doi=10.1016/s0378-5122(01)00283-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11716989  }} </ref>
*In 1990 there were 467 million [[postmenopausal]] women in the world, by 2030, [[menopausal]] [[women]] are projected to increase to 1.2 billion worldwide.<ref name="pmid8735350">{{cite journal| author=Hill K| title=The demography of menopause. | journal=Maturitas | year= 1996 | volume= 23 | issue= 2 | pages= 113-27 | pmid=8735350 | doi=10.1016/0378-5122(95)00968-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8735350  }} </ref>
*The [[prevalence]] of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] differ in [[women]] according to areas and countries that they live them, the [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms]  ranges from 74% of [[women]] in Europe, 36-50% in North America, 45-69% in [[Latin America]] and 22-63% in Asia.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868  }} </ref>
*The [[prevalence]] of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] among [[women]] prescribed [[hormone therapy]] ([[Hormonal therapy|HT]]), the mean age of patients was 54 years. The most common [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] were: [[hot flushes]] (40 %), [[night sweats]] (17 %), [[insomnia]] (16 %), [[vaginal dryness]] (13 %), [[mood disorders]] (12 %), and [[weight gain]] (12 %).
*85 % of [[postmenopausal]] [[women]] have experienced a [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptom] in their lifetime, and the prevalence of [https://www.contemporaryobgyn.net/view/managing-menopause-part-1-vasomotor-symptoms vasomotor symptoms]( [[hot flushes]] and/or [[night sweats]]) alone is estimated at approximately 40 to 50 million [[women]] in the [[United States]].<ref name="pmid26271251">{{cite journal| author=Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R | display-authors=etal| title=Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records. | journal=BMC Womens Health | year= 2015 | volume= 15 | issue=  | pages= 58 | pmid=26271251 | doi=10.1186/s12905-015-0217-y | pmc=4542113 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26271251  }} </ref>
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===Age===
*The onset [[age]] of [[menopause]] between the [[Age|ages]] of 50-53 in Europe.
*In North America, the onset [[age]] of [[menopause]] from 50-51years.
*In [[Latin America]], the onset [[age]] of [[menopause]] from 44- 53 years.
*In Asia, the onset [[age]] of [[menopause]] from 42-49 years.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868  }} </ref>
===Mortality rate===
*In 1997, the [[Fatality rate|fatality]] cases were 345 cases per 3191 [[women]] aged between 50-86 years in the [[United States]] over a mean follow-up time of 4.0 years.
*The [[Mortality ratio|mortality rate ratio]] ([[Mortality ratio|MRR]]) was 1.50% for [[women]] with [[menopause]] at [[age]] < 40, and the [[Mortality ratio|MRR]] of [[women]] with [[menopause]] at age 40-44 was 1.04%. While the [[Mortality ratio|MRR]] for [[women]] with [[menopause]] at age 45-49 was 0.96%.<ref name="pmid9590601">{{cite journal| author=Cooper GS, Sandler DP| title=Age at natural menopause and mortality. | journal=Ann Epidemiol | year= 1998 | volume= 8 | issue= 4 | pages= 229-35 | pmid=9590601 | doi=10.1016/s1047-2797(97)00207-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9590601  }} </ref>
===Race===
*The [[prevalence]] of [[menopause]] does not vary by race.
*The [[Ethnic group|ethnic]] differences in the [[symptoms]] experienced during the [[menopausal]] transition were noted. Asian [[women]] had experienced the smallest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with all other [[Ethnic group|ethnic groups]], but  African American [[women]] had experienced the largest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with other [[Ethnic group|ethnic groups]].<ref name="pmid19245351">{{cite journal| author=Green R, Santoro N| title=Menopausal symptoms and ethnicity: the Study of Women's Health Across the Nation. | journal=Womens Health (Lond) | year= 2009 | volume= 5 | issue= 2 | pages= 127-33 | pmid=19245351 | doi=10.2217/17455057.5.2.127 | pmc=3270699 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19245351  }} </ref>
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==References==
==References==
{{reflist|2}}
{{reflist|2}}
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Latest revision as of 07:45, 11 February 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]


Overview

The prevalence of menopause is estimated to be about 50 million cases annually. Menopause naturally occurs in women between 49 to 52 of age the average. The fatality cases were 345 cases per 3191 women aged between 50-86 years in the United States. There is no racial predilection to Menopause, but African American women had experienced the largest number of menopausal symptoms compared with other ethnic groups.

Epidemiology and Demographics

Prevalence and Incidence


Age

Mortality rate

Race





References

  1. Massart F, Reginster JY, Brandi ML (2001). "Genetics of menopause-associated diseases". Maturitas. 40 (2): 103–16. doi:10.1016/s0378-5122(01)00283-3. PMID 11716989.
  2. Hill K (1996). "The demography of menopause". Maturitas. 23 (2): 113–27. doi:10.1016/0378-5122(95)00968-x. PMID 8735350.
  3. 3.0 3.1 Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P (2010). "Age of menopause and impact of climacteric symptoms by geographical region". Climacteric. 13 (5): 419–28. doi:10.3109/13697137.2010.507886. PMID 20690868.
  4. Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R; et al. (2015). "Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records". BMC Womens Health. 15: 58. doi:10.1186/s12905-015-0217-y. PMC 4542113. PMID 26271251.
  5. Cooper GS, Sandler DP (1998). "Age at natural menopause and mortality". Ann Epidemiol. 8 (4): 229–35. doi:10.1016/s1047-2797(97)00207-x. PMID 9590601.
  6. Green R, Santoro N (2009). "Menopausal symptoms and ethnicity: the Study of Women's Health Across the Nation". Womens Health (Lond). 5 (2): 127–33. doi:10.2217/17455057.5.2.127. PMC 3270699. PMID 19245351.


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