Membranoproliferative glomerulonephritis (patient information)

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Overview

Membranoproliferative glomerulonephritis ( MPGN ), also known as mesangiocapillary glomerulonephritis, is a type of  glomerulonephritis and an uncommon cause of chronic nephritis caused by dense deposits in the kidney glomerular mesangium. It can be subdivided into secondary and idiopathic forms, which can distinguished by clinical features, laboratory data and renal histopathology. Membranoproliferative glomerulonephritis is a type of  glomerulonephritis (GN), which can happen due to malfunction of immune system. Each individual immune system is responsible for fight against infections or other kind of disease to maintain health, inversely in autoimmune disorders such as MPGN, immune system starts to attack healthy cell same as what happen in MPGN and eventuate in destruction of kidney glomeruli.