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===Complications===
===Complications===
*Common complications of megaloblastic anemia include:
*Common complications of megaloblastic anemia include:<ref name="pmid16988104">{{cite journal |vauthors=Aslinia F, Mazza JJ, Yale SH |title=Megaloblastic anemia and other causes of macrocytosis |journal=Clin Med Res |volume=4 |issue=3 |pages=236–41 |date=September 2006 |pmid=16988104 |pmc=1570488 |doi= |url=}}</ref>
**
**
**[[Subacute combined degeneration of spinal cord]]
**[[Subacute combined degeneration of spinal cord]]
**[[Pyrexia of unknown origin]]<ref name="pmid27847889">{{cite journal |vauthors=Siddiqui B, Rabindranath D, Faridi SH, Khan AA, Haiyat S, Eswaran R |title=Megaloblastic anemia: A common but often neglected cause of pyrexia of unknown origin |journal=J Transl Int Med |volume=3 |issue=2 |pages=64–67 |date=2015 |pmid=27847889 |pmc=4936446 |doi=10.1515/jtim-2015-0005 |url=}}</ref>
**[[Pyrexia of unknown origin]]<ref name="pmid27847889">{{cite journal |vauthors=Siddiqui B, Rabindranath D, Faridi SH, Khan AA, Haiyat S, Eswaran R |title=Megaloblastic anemia: A common but often neglected cause of pyrexia of unknown origin |journal=J Transl Int Med |volume=3 |issue=2 |pages=64–67 |date=2015 |pmid=27847889 |pmc=4936446 |doi=10.1515/jtim-2015-0005 |url=}}</ref>
**Damage to the nervous system
**Long-term neurologic complications.
**[[Peripheral neuropathy]]
**[[Dementia]].


===Prognosis===
===Prognosis===

Revision as of 13:42, 19 October 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of megaloblastic anemia include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of megaloblastic anemia typically develop ___ years after exposure to ___.
  • If left untreated, [#]% of patients with megaloblastic anemia may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with megaloblastic anemia is approximately [--]%.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. Aslinia F, Mazza JJ, Yale SH (September 2006). "Megaloblastic anemia and other causes of macrocytosis". Clin Med Res. 4 (3): 236–41. PMC 1570488. PMID 16988104.
  2. Siddiqui B, Rabindranath D, Faridi SH, Khan AA, Haiyat S, Eswaran R (2015). "Megaloblastic anemia: A common but often neglected cause of pyrexia of unknown origin". J Transl Int Med. 3 (2): 64–67. doi:10.1515/jtim-2015-0005. PMC 4936446. PMID 27847889.

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