MOS (gene): Difference between revisions

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Revision as of 06:45, 4 September 2017

Proto-oncogene serine/threonine-protein kinase mos is an enzyme that in humans is encoded by the MOS gene.^[1]^[2]

Interactions

MOS (gene) has been shown to interact with MyoD.^[3]

References

↑ Singh B, Arlinghaus RB (May 1998). "Mos and the cell cycle". Prog Cell Cycle Res. 3: 251–9. doi:10.1007/978-1-4615-5371-7_20. PMID 9552420.
↑ "Entrez Gene: MOS v-mos Moloney murine sarcoma viral oncogene homolog".
↑ Lenormand, J L; Benayoun B; Guillier M; Vandromme M; Leibovitch M P; Leibovitch S A (Feb 1997). "Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins". Mol. Cell. Biol. UNITED STATES. 17 (2): 584–93. doi:10.1128/mcb.17.2.584. ISSN 0270-7306. PMC 231783. PMID 9001211.

Sagata N (1997). "What does Mos do in oocytes and somatic cells?". BioEssays. 19 (1): 13–21. doi:10.1002/bies.950190105. PMID 9008413.
Caubet JF, Mathieu-Mahul D, Bernheim A, et al. (1986). "Human proto-oncogene c-mos maps to 8q11". EMBO J. 4 (9): 2245–8. PMC 554492. PMID 3000766.
Watson R, Oskarsson M, Vande Woude GF (1982). "Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus". Proc. Natl. Acad. Sci. U.S.A. 79 (13): 4078–82. doi:10.1073/pnas.79.13.4078. PMC 346580. PMID 6287464.
Heikinheimo O, Lanzendorf SE, Baka SG, Gibbons WE (1995). "Cell cycle genes c-mos and cyclin-B1 are expressed in a specific pattern in human oocytes and preimplantation embryos". Hum. Reprod. 10 (3): 699–707. PMID 7540181.
Lenormand JL, Benayoun B, Guillier M, et al. (1997). "Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins". Mol. Cell. Biol. 17 (2): 584–93. doi:10.1128/mcb.17.2.584. PMC 231783. PMID 9001211.
Liu H, Vuyyuru VB, Pham CD, et al. (1999). "Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association". Oncogene. 18 (23): 3461–70. doi:10.1038/sj.onc.1202699. PMID 10376524.
Pham CD, Vuyyuru VB, Yang Y, et al. (1999). "Evidence for an important role of serine 16 and its phosphorylation in the stabilization of c-Mos". Oncogene. 18 (30): 4287–94. doi:10.1038/sj.onc.1202804. PMID 10439036.
Proikas-Cezanne T, Stabel S, Riethmacher D (2002). "Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos". BMC Biochem. 3: 6. doi:10.1186/1471-2091-3-6. PMC 102758. PMID 12022922.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry". Proteomics. 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kalejs M, Ivanov A, Plakhins G, et al. (2006). "Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe". BMC Cancer. 6: 6. doi:10.1186/1471-2407-6-6. PMC 1351196. PMID 16401344.

This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it.

[pmid9552420-1] Singh B, Arlinghaus RB (May 1998). "Mos and the cell cycle". Prog Cell Cycle Res. 3: 251–9. doi:10.1007/978-1-4615-5371-7_20. PMID 9552420.

[entrez-2] "Entrez Gene: MOS v-mos Moloney murine sarcoma viral oncogene homolog".

[pmid9001211-3] Lenormand, J L; Benayoun B; Guillier M; Vandromme M; Leibovitch M P; Leibovitch S A (Feb 1997). "Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins". Mol. Cell. Biol. UNITED STATES. 17 (2): 584–93. doi:10.1128/mcb.17.2.584. ISSN 0270-7306. PMC 231783. PMID 9001211.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Proto-oncogene serine/threonine-protein kinase mos''' is an [[enzyme]] that in humans is encoded by the ''MOS'' [[gene]].<ref name="pmid9552420">{{cite journal |vauthors=Singh B, Arlinghaus RB | title = Mos and the cell cycle | journal = Prog Cell Cycle Res | volume = 3 | issue =  | pages = 251–9 |date=May 1998 | pmid = 9552420 | pmc =  | doi =  10.1007/978-1-4615-5371-7_20}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MOS v-mos Moloney murine sarcoma viral oncogene homolog| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4342| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = V-mos Moloney murine sarcoma viral oncogene homolog
- | HGNCid = 7199
- | Symbol = MOS
- | AltSymbols =; MGC119962; MGC119963; MSV
- | OMIM = 190060
- | ECnumber =
- | Homologene = 3919
- | MGIid = 97052
- | GeneAtlas_image1 = PBB_GE_MOS_221367_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0004674 |text = protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016740 |text = transferase activity}}
- | Component =
- | Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 4342
-    | Hs_Ensembl = ENSG00000172680
-    | Hs_RefseqProtein = NP_005363
-    | Hs_RefseqmRNA = NM_005372
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 8
-    | Hs_GenLoc_start = 57188055
-    | Hs_GenLoc_end = 57189095
-    | Hs_Uniprot = P00540
-    | Mm_EntrezGene = 17451
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA = XM_973427
-    | Mm_RefseqProtein = XP_978521
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''V-mos Moloney murine sarcoma viral oncogene homolog''', also known as '''MOS''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MOS v-mos Moloney murine sarcoma viral oncogene homolog| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4342| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 53: / Line 7: @@
 | summary_text =
 }}
+==Interactions==
+MOS (gene) has been shown to [[Protein-protein interaction|interact]] with [[MyoD]].<ref name=pmid9001211>{{cite journal |last=Lenormand |first=J L |authorlink= |author2=Benayoun B |author3=Guillier M |author4=Vandromme M |author5=Leibovitch M P |author6=Leibovitch S A  |date=Feb 1997 |title=Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins |journal=Mol. Cell. Biol. |volume=17 |issue=2 |pages=584–93 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 9001211 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=231783 | doi=10.1128/mcb.17.2.584}}</ref>
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Sagata N |title=What does Mos do in oocytes and somatic cells? |journal=Bioessays |volume=19 |issue= 1 |pages= 13-21 |year= 1997 |pmid= 9008413 |doi= 10.1002/bies.950190105 }}
+*{{cite journal  | author=Sagata N |title=What does Mos do in oocytes and somatic cells? |journal=BioEssays |volume=19 |issue= 1 |pages= 13–21 |year= 1997 |pmid= 9008413 |doi= 10.1002/bies.950190105 }}
-*{{cite journal  | author=Singh B, Arlinghaus RB |title=Mos and the cell cycle. |journal=Progress in cell cycle research |volume=3 |issue=  |pages= 251-9 |year= 1998 |pmid= 9552420 |doi=  }}
+*{{cite journal   |vauthors=Caubet JF, Mathieu-Mahul D, Bernheim A, etal |title=Human proto-oncogene c-mos maps to 8q11. |journal=EMBO J. |volume=4 |issue= 9 |pages= 2245–8 |year= 1986 |pmid= 3000766 |doi=  | pmc=554492  }}
-*{{cite journal  | author=Caubet JF, Mathieu-Mahul D, Bernheim A, ''et al.'' |title=Human proto-oncogene c-mos maps to 8q11. |journal=EMBO J. |volume=4 |issue= 9 |pages= 2245-8 |year= 1986 |pmid= 3000766 |doi=  }}
+*{{cite journal  |vauthors=Watson R, Oskarsson M, Vande Woude GF |title=Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=79 |issue= 13 |pages= 4078–82 |year= 1982 |pmid= 6287464 |doi=10.1073/pnas.79.13.4078  | pmc=346580  }}
-*{{cite journal  | author=Watson R, Oskarsson M, Vande Woude GF |title=Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=79 |issue= 13 |pages= 4078-82 |year= 1982 |pmid= 6287464 |doi=  }}
+*{{cite journal  |vauthors=Heikinheimo O, Lanzendorf SE, Baka SG, Gibbons WE |title=Cell cycle genes c-mos and cyclin-B1 are expressed in a specific pattern in human oocytes and preimplantation embryos. |journal=Hum. Reprod. |volume=10 |issue= 3 |pages= 699–707 |year= 1995 |pmid= 7540181 |doi=  }}
-*{{cite journal  | author=Heikinheimo O, Lanzendorf SE, Baka SG, Gibbons WE |title=Cell cycle genes c-mos and cyclin-B1 are expressed in a specific pattern in human oocytes and preimplantation embryos. |journal=Hum. Reprod. |volume=10 |issue= 3 |pages= 699-707 |year= 1995 |pmid= 7540181 |doi=  }}
+*{{cite journal   |vauthors=Lenormand JL, Benayoun B, Guillier M, etal |title=Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins. |journal=Mol. Cell. Biol. |volume=17 |issue= 2 |pages= 584–93 |year= 1997 |pmid= 9001211 |doi=  10.1128/mcb.17.2.584| pmc=231783  }}
-*{{cite journal  | author=Lenormand JL, Benayoun B, Guillier M, ''et al.'' |title=Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins. |journal=Mol. Cell. Biol. |volume=17 |issue= 2 |pages= 584-93 |year= 1997 |pmid= 9001211 |doi=  }}
+*{{cite journal   |vauthors=Liu H, Vuyyuru VB, Pham CD, etal |title=Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association. |journal=Oncogene |volume=18 |issue= 23 |pages= 3461–70 |year= 1999 |pmid= 10376524 |doi= 10.1038/sj.onc.1202699 }}
-*{{cite journal  | author=Liu H, Vuyyuru VB, Pham CD, ''et al.'' |title=Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association. |journal=Oncogene |volume=18 |issue= 23 |pages= 3461-70 |year= 1999 |pmid= 10376524 |doi= 10.1038/sj.onc.1202699 }}
+*{{cite journal   |vauthors=Pham CD, Vuyyuru VB, Yang Y, etal |title=Evidence for an important role of serine 16 and its phosphorylation in the stabilization of c-Mos. |journal=Oncogene |volume=18 |issue= 30 |pages= 4287–94 |year= 1999 |pmid= 10439036 |doi= 10.1038/sj.onc.1202804 }}
-*{{cite journal  | author=Pham CD, Vuyyuru VB, Yang Y, ''et al.'' |title=Evidence for an important role of serine 16 and its phosphorylation in the stabilization of c-Mos. |journal=Oncogene |volume=18 |issue= 30 |pages= 4287-94 |year= 1999 |pmid= 10439036 |doi= 10.1038/sj.onc.1202804 }}
+*{{cite journal  |vauthors=Proikas-Cezanne T, Stabel S, Riethmacher D |title=Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos. |journal=BMC Biochem. |volume=3|pages= 6 |year= 2002 |pmid= 12022922 |doi=10.1186/1471-2091-3-6  | pmc=102758  }}
-*{{cite journal  | author=Proikas-Cezanne T, Stabel S, Riethmacher D |title=Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos. |journal=BMC Biochem. |volume=3 |issue=  |pages= 6 |year= 2002 |pmid= 12022922 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Hassel S, Eichner A, Yakymovych M, etal |title=Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. |journal=Proteomics |volume=4 |issue= 5 |pages= 1346–58 |year= 2004 |pmid= 15188402 |doi= 10.1002/pmic.200300770 }}
-*{{cite journal  | author=Hassel S, Eichner A, Yakymovych M, ''et al.'' |title=Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. |journal=Proteomics |volume=4 |issue= 5 |pages= 1346-58 |year= 2004 |pmid= 15188402 |doi= 10.1002/pmic.200300770 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Kalejs M, Ivanov A, Plakhins G, etal |title=Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. |journal=BMC Cancer |volume=6|pages= 6 |year= 2006 |pmid= 16401344 |doi= 10.1186/1471-2407-6-6  | pmc=1351196 }}
-*{{cite journal  | author=Kalejs M, Ivanov A, Plakhins G, ''et al.'' |title=Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. |journal=BMC Cancer |volume=6 |issue=  |pages= 6 |year= 2006 |pmid= 16401344 |doi= 10.1186/1471-2407-6-6 }}
 }}
 {{refend}}
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MOS (gene): Difference between revisions

Revision as of 06:45, 4 September 2017

Interactions

References

Further reading

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