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Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX (mohawk homeobox) gene.[1]
Function
MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.[1][2]
↑Anderson DM, Arredondo J, Hahn K, Valente G, Martin JF, Wilson-Rawls J, Rawls A (March 2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID16408284.
Further reading
Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1994). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID7829101.
Weinmann A, Galle PR, Teufel A (2005). "In silico characterization of an Iroquois family-related homeodomain protein". Int. J. Mol. Med. 16 (3): 443–8. doi:10.3892/ijmm.16.3.443. PMID16077953.
Anderson DM, Arredondo J, Hahn K, et al. (2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID16408284.
Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell. Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID18029348.