Lupus nephritis classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2], Raviteja Guddeti, M.B.B.S. [3]

Overview

Classification

The World Health Organization has divided lupus nephritis into five classes based on the biopsy.

  • Class I is histologically normal and does not show any evidence of disease.
  • Class II is based on a finding of mesangial lupus nephritis
  • Class III is focal proliferative nephritis
  • Class IV is diffuse proliferative nephritis
  • Class V is membranous nephritis and is characterized by extreme edema and protein loss.
  • Class VI Glomerulosclerosis

References

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