Irritable bowel syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no other diagnostic studies associated with [disease name].

OR

[Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

Endoscopy

In young patients with symptoms of classic IBS, additional invasive investigations such as endoscopy are not required and increase patient dissatisfaction. However, endoscopic evaluation is performed for the following indications:[1]

  • Gastrointestinal endoscopy is done in difficult cases of IBS where history is unclear but the physical examination is suggestive of the diagnosis.
  • All IBS patients with alarm features must undergo endoscopic evaluation.
  • Colonoscopy must be considered in patients aged more than 50 years as part of routine colon cancer screening.
  • In IBS patients with persistent diarrhea of age >40 years, a colonoscopy should also be performed to rule out organic causes like IBD and perform biopsies.
  • IBS patients with dyspepsia should undergo esophagogastroduodenoscopy.
  • Sigmoidoscopy is performed in patients in order to exclude melanosis coli due to laxative abuse and microinflammation.
  • Sigmoid colon biopsies and duodenal biopsies are required for exclusion of microscopic colitis, Crohn's disease, and celiac disease.

Anorectal manometry

Anorectal manometry rules out obstructive defecation (pelvic-floor dyssynergia).

References

  1. Begtrup LM, Engsbro AL, Kjeldsen J, Larsen PV, Schaffalitzky de Muckadell O, Bytzer P, Jarbøl DE (2013). "A positive diagnostic strategy is noninferior to a strategy of exclusion for patients with irritable bowel syndrome". Clin. Gastroenterol. Hepatol. 11 (8): 956–62.e1. doi:10.1016/j.cgh.2012.12.038. PMID 23357491.

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