Idiopathic thrombocytopenic purpura natural history, complications and prognosis
{{ITP} Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
More than 70% of the cases in children end up in remission within 6 months whether treated or not.[1][2][3] Moreover, a third of the remaining chronic cases remitted during the follow-up observation, and another third ended up with only mild thrombocytopenia (>50,000 platelets per μL).[1].
Complications
Subarachnoid, intracerebral hemorrhage or other internal bleeding are very serious possible complications of this disease. Fortunately, these are unlikely in patients with the platelets count above 20,000.
Prognosis
References
- ↑ 1.0 1.1 Watts RG (2004). "Idiopathic thrombocytopenic purpura: a 10-year natural history study at the children's hospital of alabama". Clinical pediatrics. 43 (8): 691–702. PMID 15494875.
- ↑ Treutiger I, Rajantie J, Zeller B, Henter JI, Elinder G, Rosthøj S (2007). "Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity?". Arch. Dis. Child. 92 (8): 704–7. doi:10.1136/adc.2006.098442. PMID 17460024.
- ↑ Ou CY, Hsieh KS, Chiou YH, Chang YH, Ger LP (2006). "A comparative study of initial use of intravenous immunoglobulin and prednisolone treatments in childhood idiopathic thrombocytopenic purpur". Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi. 47 (5): 226–31. PMID 17352309.