Hyperosmolar hyperglycemic state diagnostic study of choice: Difference between revisions

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{{Hyperosmolar hyperglycemic state}}
{{Hyperosmolar hyperglycemic state}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{HS}}  
==Overview==
==Overview==
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
There are specific cut-offs for [[serum glucose]] level, [[ketone]] levels, body [[pH]], [[serum bicarbonate]] levels and [[anion gap]] for the diagnosis of the hyperosmolar hyperglycemic state as outlined by the [[American Diabetes Association]].


OR
The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
OR
The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
OR
There are no established criteria for the diagnosis of [disease name].
==Diagnostic Criteria==
==Diagnostic Criteria==
*The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:  
The diagnosis of hyperosmolar hyperglycemic state is based on the following features/criteria:<ref name="urlwww.aace.com">{{cite web |url=https://www.aace.com/files/position-statements/SGLT-2-position-statement.pdf |title=www.aace.com |format= |work= |accessdate=}}</ref><ref name="pmid25342831">{{cite journal| author=Pasquel FJ, Umpierrez GE| title=Hyperosmolar hyperglycemic state: a historic review of the clinical presentation, diagnosis, and treatment. | journal=Diabetes Care | year= 2014 | volume= 37 | issue= 11 | pages= 3124-31 | pmid=25342831 | doi=10.2337/dc14-0984 | pmc=4207202 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25342831  }} </ref>
**[criterion 1]
{| class="wikitable"
**[criterion 2]
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Parameter
**[criterion 3]
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Lab value
**[criterion 4]
|-
*The diagnosis of [disease name] is based on the [criteria name] criteria, which include
|'''[[Serum]] [[glucose]]'''
**[criterion 1]
|
**[criterion 2]
* > 600 mg/dl
**[criterion 3]
|-
*The diagnosis of [disease name] is based on the [definition name] definition, which includes
|'''[[Serum]] [[osmolality]]'''
**[criterion 1]
|
**[criterion 2]
* > 320 mOsm/kg
**[criterion 3]
|-
OR
|'''[[Arterial]] [[ph]]'''
*There are no established criteria for the diagnosis of [disease name].
|
* > 7.30
|-
|'''[[Serum]] [[ketones]]'''
|
* Trace or negative
|-
|'''[[Urine]] [[ketones]]'''
|
* Trace or negative
|-
|'''[[Anion gap]]'''
|
* Variable
|-
|'''[[Mental status]]'''
|
* [[Drowsiness|Drowsy]]
* [[Stupor]]
* [[Coma]] in moderate to severe HHS
|}


==References==
==References==

Revision as of 19:59, 23 September 2017

Hyperosmolar hyperglycemic state Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Husnain Shaukat, M.D [2]

Overview

There are specific cut-offs for serum glucose level, ketone levels, body pH, serum bicarbonate levels and anion gap for the diagnosis of the hyperosmolar hyperglycemic state as outlined by the American Diabetes Association.

Diagnostic Criteria

The diagnosis of hyperosmolar hyperglycemic state is based on the following features/criteria:[1][2]

Parameter Lab value
Serum glucose
  • > 600 mg/dl
Serum osmolality
  • > 320 mOsm/kg
Arterial ph
  • > 7.30
Serum ketones
  • Trace or negative
Urine ketones
  • Trace or negative
Anion gap
  • Variable
Mental status

References

  1. ↑ "www.aace.com" (PDF).
  2. ↑ Pasquel FJ, Umpierrez GE (2014). "Hyperosmolar hyperglycemic state: a historic review of the clinical presentation, diagnosis, and treatment". Diabetes Care. 37 (11): 3124–31. doi:10.2337/dc14-0984. PMC 4207202. PMID 25342831.

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