Hepatorenal syndrome screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are predictors for patients suffering from liver disease to view chances of development of Hepatorenal syndrome[HRS].

Screening

There are predictors for patients suffering from liver disease to view chances of development of Hepatorenal syndrome[HRS].[1][2]

Following are variables that should taken in consideration to predict HRS:[3][4]

  • Hepatomegaly
  • Oesophageal varices
  • History of ascites
  • Nutritional status
  • GFR
  • Blood urea nitrogen
  • Serum sodium and potassium
  • Plasma renin activity
  • Plasma noradrenaline
  • Serum and urinary osmolality
  • Urinary sodium excretion
  • Free water clearance after a water load
  • Mean arterial pressure 

References

  1. Sersté T, Lebrec D, Valla D, Moreau R (2008). "Incidence and characteristics of type 2 hepatorenal syndrome in patients with cirrhosis and refractory ascites". Acta Gastroenterol Belg. 71 (1): 9–14. PMID 18396743.
  2. Mathurin S, Jaimet C, Turletti C, Arosio A, González G, Kuzmicz G (2008). "[Renal failure in patients with cirrhosis and ascites: incidence, etiology and predictive factors]". Acta Gastroenterol Latinoam. 38 (2): 116–25. PMID 18697406.
  3. Ginès A, Escorsell A, Ginès P, Saló J, Jiménez W, Inglada L; et al. (1993). "Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites". Gastroenterology. 105 (1): 229–36. PMID 8514039.
  4. Moreau R (1994). "[Hepatorenal syndrome: incidence, predictive factors and prognosis]". Gastroenterol Clin Biol. 18 (5): 541–3. PMID 7813880.

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