Hepatorenal syndrome epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
Hepatorenal syndrome{HRS} is common in cirrhotic patients


==Epidemiology and Demographics==
==Epidemiology and Demographics==
It is estimated that 39% of patients with [[cirrhosis]] and [[ascites]] will develop hepatorenal syndrome within five years of the onset of their disease. The prognosis of these patients is grim with untreated patients having an extremely short survival, and with the severity of liver disease (as evidenced by the [[Model for End-Stage Liver Disease|MELD]] score) now believed to determine outcome.<ref>Alessandria C, Ozdogan O, Guevara M, Restuccia T, Jimenez W, Arroyo V, Rodes J, Gines P.  MELD score and clinical type predict prognosis in hepatorenal syndrome: Relevance to liver transplantation. ''Hepatology'' 2005 Jun;41(6):1282-9. PMID 15834937</ref>  Some patients without cirrhosis develop hepatorenal syndrome, with an incidence of about 20% seen in one study of ill patients with [[alcoholic hepatitis]].<ref>Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. ''Gastroenterology'' 2000 Dec;119(6):1637-48PMID 11113085.</ref>
'''Incidence:'''
 
In 1993, incidance of HRS had an incidence of 18% at one year and 39% at five years in patients with cirrhosis and ascites.<ref name="pmid8514039">{{cite journal| author=Ginès A, Escorsell A, Ginès P, Saló J, Jiménez W, Inglada L et al.| title=Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites. | journal=Gastroenterology | year= 1993 | volume= 105 | issue= 1 | pages= 229-36 | pmid=8514039 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8514039 }}</ref>


==References==
==References==

Revision as of 16:15, 5 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]

Overview

Hepatorenal syndrome{HRS} is common in cirrhotic patients

Epidemiology and Demographics

Incidence:

In 1993, incidance of HRS had an incidence of 18% at one year and 39% at five years in patients with cirrhosis and ascites.[1]

References

  1. Ginès A, Escorsell A, Ginès P, Saló J, Jiménez W, Inglada L; et al. (1993). "Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites". Gastroenterology. 105 (1): 229–36. PMID 8514039.

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