Hepatoblastoma: Difference between revisions
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==Overview== | ==Overview== | ||
'''Hepatoblastoma''' is an uncommon malignant liver neoplasm occurring in infants and children and composed of tissue resembling fetal or mature liver cells or [[bile duct]]s. They usually present with an [[abdominal mass]]. | '''Hepatoblastoma''' is an uncommon malignant liver neoplasm occurring in infants and children and composed of tissue resembling fetal or mature liver cells or [[bile duct]]s. They usually present with an [[abdominal mass]]. [[Alpha-fetoprotein]] (AFP) commonly is elevated, but when AFP is not elevated at diagnosis the prognosis is poor.<ref name="pmid18166449">{{cite journal | ||
| author = De Ioris M, Brugieres L, Zimmermann A, Keeling J, Brock P, Maibach R, Pritchard J, Shafford L, Zsiros J, Czaudzerna P, Perilongo G | |||
| title = Hepatoblastoma with a low serum alpha-fetoprotein level at diagnosis: The SIOPEL group experience. | |||
| journal = Eur J Cancer | |||
| volume = 44 | |||
| issue = | |||
| pages = 545 | |||
| year = 2007 | |||
| pmid = 18166449 | |||
| doi = 10.1016/j.ejca.2007.11.022 | |||
| issn = | |||
}}</ref> | |||
==Treatment== | ==Treatment== | ||
Surgical resection, adjuvant chemotherapy prior to resection, and [[liver transplantation]] have been used to treat these neoplasms. | Surgical resection, adjuvant chemotherapy prior to resection, and [[liver transplantation]] have been used to treat these neoplasms. | ||
Revision as of 02:01, 14 January 2009
| Hepatoblastoma | |
| ICD-10 | C22.0 |
|---|---|
| ICD-O: | 8970/3 |
| DiseasesDB | 5799 |
| eMedicine | ped/982 radio/331 |
| MeSH | D018197 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Hepatoblastoma is an uncommon malignant liver neoplasm occurring in infants and children and composed of tissue resembling fetal or mature liver cells or bile ducts. They usually present with an abdominal mass. Alpha-fetoprotein (AFP) commonly is elevated, but when AFP is not elevated at diagnosis the prognosis is poor.[1]
Treatment
Surgical resection, adjuvant chemotherapy prior to resection, and liver transplantation have been used to treat these neoplasms.
External links
- University of Minnesota hepatoblastoma epidemiology study
- Hepatoblastoma Support Group
- One Little Girl's Fight against Hepatoblastoma
- ↑ De Ioris M, Brugieres L, Zimmermann A, Keeling J, Brock P, Maibach R, Pritchard J, Shafford L, Zsiros J, Czaudzerna P, Perilongo G (2007). "Hepatoblastoma with a low serum alpha-fetoprotein level at diagnosis: The SIOPEL group experience". Eur J Cancer. 44: 545. doi:10.1016/j.ejca.2007.11.022. PMID 18166449.