Hepatitis laboratory findings: Difference between revisions
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{{Hepatitis}} | {{Hepatitis}} | ||
{{ | {{CMG}} | ||
==Lab Tests== | |||
*Hepatitis typically causes a rise in [[liver function tests]]. In particular, there is often a disproportionate rise in transaminases relative to the [[alkaline phosphatase]], but this is not universal and the pattern can be suggestive of cause. Furthermore, [[primary sclerosing cholangitis]] can sometimes overlap with [[autoimmune hepatitis]]. | |||
===Immunology=== | |||
This tends to be most useful when by exclusion [[autoimmune hepatitis]] is being considered and the following are necessary as components of a validated probability score<ref>[http://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=19452572 Czaja AJ, Bayraktar Y. Non-classical phenotypes of autoimmune hepatitis and advances in diagnosis and treatment. World journal of gastroenterology : WJG. 2009 May 21; 15(19):2314-28.]</ref> | |||
*Autoantibodies | |||
**Antinuclear | |||
**Anti-smooth-muscle | |||
**Microsome type 1 | |||
**Soluble liver antigen | |||
*Serum IgG | |||
== References == | == References == | ||
Revision as of 18:59, 10 February 2012
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Hepatitis Main Page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Lab Tests
- Hepatitis typically causes a rise in liver function tests. In particular, there is often a disproportionate rise in transaminases relative to the alkaline phosphatase, but this is not universal and the pattern can be suggestive of cause. Furthermore, primary sclerosing cholangitis can sometimes overlap with autoimmune hepatitis.
Immunology
This tends to be most useful when by exclusion autoimmune hepatitis is being considered and the following are necessary as components of a validated probability score[1]
- Autoantibodies
- Antinuclear
- Anti-smooth-muscle
- Microsome type 1
- Soluble liver antigen
- Serum IgG