Heparin-induced thrombocytopenia cost-effectiveness of therapy
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aric C. Hall, M.D., [3], Shyam Patel [4]
Overview
Cost-Effectiveness of Therapy
The treatment of HIT involves use of alternative anticoagulants, such as direct thrombin inhibitors. However, there is also data for use of the factor X inhibitor fondaparinux, which is less expensive than direct thrombin inhibitors.[1] Fondaparinux would found to be the most cost-effective agent for treatment of HIT, compared to argatroban or bivalirudin. [1]
| Characteristic/Parameter | Argatroban | Bivalirudin | Fondaparinux | ||||
|---|---|---|---|---|---|---|---|
| Cost of administration | $411.43 | $411.43 | $25.40 | ||||
| Average wholesale price | $1194.65 (1 vial of 250mg) | $753.07 (1 vial of 250mg) | $220.34 (1 syringe of 7.5mg) | Total cost for 9 days of therapy | $1326 | $1562 | $164 |
References
- ↑ 1.0 1.1 Aljabri A, Huckleberry Y, Karnes JH, Gharaibeh M, Kutbi HI, Raz Y; et al. (2016). "Cost-effectiveness of anticoagulants for suspected heparin-induced thrombocytopenia in the United States". Blood. 128 (26): 3043–3051. doi:10.1182/blood-2016-07-728030. PMID PMID27793877 Check
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