Heparin-induced thrombocytopenia causes: Difference between revisions
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==Causes== | ==Causes== | ||
* Duration of heparin treatment | * HIT is always caused by exogenous heparin or heparinoid exposure. | ||
* The type of heparin involved | * Duration of heparin treatment: long duration, up to 2 weeks is associated with the greatest risk.<ref name="pmid23714311">{{cite journal| author=Lee GM, Arepally GM| title=Diagnosis and management of heparin-induced thrombocytopenia. | journal=Hematol Oncol Clin North Am | year= 2013 | volume= 27 | issue= 3 | pages= 541-63 | pmid=23714311 | doi=10.1016/j.hoc.2013.02.001 | pmc=3668315 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23714311 }} </ref> | ||
* The type of patient | * The type of heparin involved: unfractionated heparin[[UFH]] has a greater risk than [[low molecular weight heparin]] LMWH.<ref name="pmid23714311">{{cite journal| author=Lee GM, Arepally GM| title=Diagnosis and management of heparin-induced thrombocytopenia. | journal=Hematol Oncol Clin North Am | year= 2013 | volume= 27 | issue= 3 | pages= 541-63 | pmid=23714311 | doi=10.1016/j.hoc.2013.02.001 | pmc=3668315 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23714311 }} </ref> | ||
* Females have a higher risk. | * The type of patient: surgical patients are at higher risk than medical; cardiac surgical patients have the highest risk of all.<ref name="pmid23714311">{{cite journal| author=Lee GM, Arepally GM| title=Diagnosis and management of heparin-induced thrombocytopenia. | journal=Hematol Oncol Clin North Am | year= 2013 | volume= 27 | issue= 3 | pages= 541-63 | pmid=23714311 | doi=10.1016/j.hoc.2013.02.001 | pmc=3668315 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23714311 }} </ref> | ||
* Gender: Females have a higher risk of HIT than males. | |||
==Reference== | ==Reference== | ||
Revision as of 06:00, 13 July 2017
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Heparin-induced thrombocytopenia causes On the Web |
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American Roentgen Ray Society Images of Heparin-induced thrombocytopenia causes |
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Directions to Hospitals Treating Heparin-induced thrombocytopenia |
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Risk calculators and risk factors for Heparin-induced thrombocytopenia causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aric C. Hall, M.D., [3]
Overview
Heparin-induced thrombocytopenia is diagnosed when the platelet count falls by > 50% typically after 5-10 days of heparin therapy. The causes of the condition depends on type of heparin (unfractionated heparin > low molecular weight heparin), duration of therapy, females and type of patients (commoner in surgical patients that require large amount of heparin)
Causes
- HIT is always caused by exogenous heparin or heparinoid exposure.
- Duration of heparin treatment: long duration, up to 2 weeks is associated with the greatest risk.[1]
- The type of heparin involved: unfractionated heparinUFH has a greater risk than low molecular weight heparin LMWH.[1]
- The type of patient: surgical patients are at higher risk than medical; cardiac surgical patients have the highest risk of all.[1]
- Gender: Females have a higher risk of HIT than males.
Reference
- ↑ 1.0 1.1 1.2 Lee GM, Arepally GM (2013). "Diagnosis and management of heparin-induced thrombocytopenia". Hematol Oncol Clin North Am. 27 (3): 541–63. doi:10.1016/j.hoc.2013.02.001. PMC 3668315. PMID 23714311.