Heparin-induced thrombocytopenia causes: Difference between revisions

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{{Heparin-induced thrombocytopenia}}
{{Heparin-induced thrombocytopenia}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}, Aric C. Hall, M.D., [mailto:achall@bidmc.harvard.edu]
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}, Aric C. Hall, M.D., [mailto:achall@bidmc.harvard.edu]
==Overview==
==Overview==
[[Heparin-induced thrombocytopenia]] is diagnosed when the [[platelet]] count falls by > 50% typically after 5-10 days of [[heparin]] therapy. The causes of the condition depends on type of heparin ([[unfractionated heparin]] > [[low molecular weight heparin]]), duration of therapy, females and type of patients (commoner in surgical patients that require large amount of heparin)
[[Heparin-induced thrombocytopenia]] is diagnosed when the [[platelet]] count falls by > 50% typically after 5-10 days of [[heparin]] therapy. The causes of the condition depends on type of heparin ([[unfractionated heparin]] > [[low molecular weight heparin]]), duration of therapy, females and type of patients (commoner in surgical patients that require large amount of heparin)
==Causes==
==Causes==
* Duration of heparin treatment; long duration, up to 2 weeks is associated with the greatest risk.  
* Duration of heparin treatment; long duration, up to 2 weeks is associated with the greatest risk.  
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Revision as of 19:40, 17 June 2016

Heparin-induced thrombocytopenia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aric C. Hall, M.D., [3]

Overview

Heparin-induced thrombocytopenia is diagnosed when the platelet count falls by > 50% typically after 5-10 days of heparin therapy. The causes of the condition depends on type of heparin (unfractionated heparin > low molecular weight heparin), duration of therapy, females and type of patients (commoner in surgical patients that require large amount of heparin)

Causes

  • Duration of heparin treatment; long duration, up to 2 weeks is associated with the greatest risk.
  • The type of heparin involved; unfractionated heparinUFH has a greater risk than low molecular weight heparin LMWH.
  • The type of patient; surgical patients are at higher risk than medical; cardiac surgical patients have the highest risk of all.
  • Females have a higher risk.

Reference

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