Henoch-Schönlein purpura history and symptoms: Difference between revisions
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Revision as of 19:29, 27 September 2012
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Henoch-Schönlein purpura Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and symptoms
Purpura, arthritis and abdominal pain are known as the "classic triad" of Henoch-Schönlein purpura.[1] Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%. Some include gastrointestinal hemorrhage as a fourth criterion - this occurs in 33% of cases (sometimes but not necessarily due to intussusception).[2] The purpura typically appear on the legs and buttocks, but may also be seen on the arms, face and trunk. The abdominal pain is colicky in character. The joints involved tend to be the ankles, knees, and elbows but arthritis in the hands and feet is possible; the arthritis is non-erosive and hence causes no permanent deformity.[1] 40% have evidence of kidney involvement, mainly in the form of hematuria (blood in the urine), but only a quarter will have this in sufficient quantities to be noticeable without laboratory tests.[2] Problems in other organs, such as the central nervous system (brain and spinal cord) and lungs may occur, but much less commonly than the skin, bowel and kidneys.. The disease tends to last about 4 weeks, and then resolves spontaneously.
On the basis of symptoms, it is possible to distinguish HSP from hypersensitivity vasculitis (HV). In a series comparing 85 HSP patients with 93 HV patients, five symptoms were found to be indicative of HSP: palpable purpura, abdominal angina, digestive tract hemorrhage (not due to intussussception), hematuria and age less than 20. The presence of three or more of these indicators has an 87% sensitivity for predicting HSP.[3]
References
- ↑ 1.0 1.1 Kraft DM, Mckee D, Scott C (1998). "Henoch-Schönlein purpura: a review". Am Fam Physician. 58 (2): 405–8, 411. PMID 9713395.
- ↑ 2.0 2.1 Saulsbury FT (1999). "Henoch-Schönlein purpura in children. Report of 100 patients and review of the literature". Medicine (Baltimore). 78 (6): 395–409. PMID 10575422.
- ↑ Michel BA, Hunder GG, Bloch DA, Calabrese LH (1992). "Hypersensitivity vasculitis and Henoch-Schönlein purpura: a comparison between the 2 disorders". J. Rheumatol. 19 (5): 721–8. PMID 1613701.