Hemophilia history and symptoms: Difference between revisions

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Revision as of 02:08, 18 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Patients with hemophilia can present with a history of excessive bleeding after minor injuries or spontaneous bleeding. They can also report family history of hemophilia. Hemophilia when mild, can be asymptomatic. Common symptoms, when present, include epistaxis, oral mucosal bleeding, joint pain and swelling, lethargy and fatigue, excessive bleeding after dental procedures, prolonged bleeding after circumcision and muscle hematoma after vaccination.

History and Symptoms

Patients with hemophilia may have a positive history of:

Easy bruising^[1]
Unprovoked deep-seated bleeds^[1]
Prolonged excess bleeds following surgery or trauma^[1]

References

↑ ^1.0 ^1.1 ^1.2 Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A (July 2018). "Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia". Indian Pediatr. 55 (7): 582–590. PMID 30129541.

Template:WH Template:WS

[pmid30129541-1] 1.0 ^1.1 ^1.2 Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A (July 2018). "Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia". Indian Pediatr. 55 (7): 582–590. PMID 30129541.

[1]

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{Simrat}}
 ==Overview==
-Symptoms of hemophilia include excessive bleeding and easy bruising.
+Patients with hemophilia can present with a history of excessive bleeding after minor injuries or spontaneous bleeding. They can also report family history of hemophilia. Hemophilia when mild, can be asymptomatic. Common symptoms, when present, include epistaxis, oral mucosal bleeding, joint pain and swelling, lethargy and fatigue, excessive bleeding after dental procedures, prolonged bleeding after circumcision and muscle hematoma after vaccination.
-==History==
+==History and Symptoms==
-Most patients present with bleeding during the [[neonatal]] period or with bleeding large haematoma following minor [[trauma]] as a toddler. In the worst cases, bleeding occurs for no reason. Internal bleeding may occur anywhere and bleeding into joints is common.The severity of symptoms vary. Bleeding is the main symptom of the disease. It is often first seen when an infant is circumcised. Other bleeding problems are seen when the infant starts crawling and walking. Mild cases may go unnoticed until later in life. Symptoms may first occur after surgery or injury. Internal bleeding may occur anywhere. Around 70% of patients have the severe form of the disease characterized by spontaneous haemorrhage or haemorrhage following minor [[trauma]].<ref>{{Cite web | title = Wikipedia Hemophilia Symptoms| url =https://en.wikipedia.org/wiki/Haemophilia }}</ref>
+Patients with hemophilia may have a positive history of:
-==Symptoms of Hemophilia==
+*Easy bruising<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref>
-The major symptoms of hemophilia are excessive bleeding and easy bruising.
+*Unprovoked deep-seated bleeds<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref>
-===Excessive Bleeding===
+*Prolonged excess bleeds following surgery or trauma<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref>
-The extent of bleeding depends on how severe the hemophilia is.
+*
-Children who have mild hemophilia may not have signs unless they have excessive bleeding from a dental procedure, an accident, or surgery. Males who have severe hemophilia may bleed heavily after circumcision.
-Bleeding can occur on the body's surface (external bleeding) or inside the body ([[internal bleeding]]).
-Symptoms of external bleeding may include:
-*Bleeding in the mouth from a cut or bite or from cutting or losing a tooth
-*[[Nosebleeds]] for no obvious reason
-*Heavy bleeding from a minor cut
-*Bleeding from a cut that resumes after stopping for a short time
-===Bleeding in the Joints===
-Bleeding in the knees, elbows, or other joints is another common form of internal bleeding in people who have hemophilia. This bleeding can occur without obvious injury. At first, the bleeding causes tightness in the joint with no real pain or any visible signs of bleeding. The joint then becomes swollen, hot to touch, and painful to bend. Swelling continues as bleeding continues. Eventually, movement in the joint is temporarily lost. Pain can be severe. Joint bleeding that isn't treated quickly can damage the joint.
-===Bleeding in the Brain===
-[[Internal bleeding]] in the brain is a very serious complication of hemophilia. It can happen after a simple bump on the head or a more serious injury. The signs and symptoms of bleeding in the brain include:
-*Long-lasting, painful [[headaches]] or neck pain or stiffness
-*Repeated [[vomiting]]
-*Sleepiness or changes in behavior
-*Sudden [[weakness]] or clumsiness of the arms or legs or problems walking
-*[[Double vision]]
-*[[Convulsions]] or [[seizures]]<ref>{{Cite web | title = NIH Hemophilia Symptoms| url =http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/signs }}</ref>
 ==References==

Hemophilia history and symptoms: Difference between revisions

Revision as of 02:08, 18 January 2019

Overview

History and Symptoms

References

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