Hematemesis primary prevention: Difference between revisions

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{{Hematemesis}}
{{Hematemesis}}
{{CMG}} {{JFS}}
{{CMG}} {{AE}}
 
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==Overview==
==Overview==
==Primary Prevention==
 
Treatment of underlying disease is the best way to prevent hematemsis.
==Primary prevention==
===Prophylaxis Against Bleed From Variceal Hemorrhage and Ulceration ===
*Primary prophylaxis against variceal hemorrhage is indicated because of high rate of bleeding from esophageal varices and the high mortality associated with bleeding. Prophylactic [[propranolol]] or [[nadolol]] therapy is the only cost-effective therapy in this setting.
*Prophylaxis against [[stress]] ulceration maybe also indicated for ICU patients with any of the following characteristics:
#[[Coagulopathy]]
#Mechanical ventilation for more than 2 days
#History of GI ulceration or bleeding with the past year
#Two or more of the following risk factors — [[sepsis]], ICU admission lasting >1 week, occult GI bleeding lasting ≥6 days, and [[glucocorticoid]] therapy.
*Effective identification and antibiotic treatment of H.Pylori infections is also crutial in preventing complications including upper GI bleeding.
*In regards to the prevention of NSAID-related peptic ulcer disease and complicating upper GI bleed: patients are at the highest risk for NSAID-induced GI toxicity when they have any of these risk factors:
#A history of an ulcer or GI hemorrhage
#Age >60
#High dosage of a NSAID
#Concurrent use of glucocorticoids
#Concurrent use of anticoagulants
In these patients, the use of COX-2 selective inhibitor or a nonselective NSAID in combination with a PPI or misoprostol is indicated.
In addition, patients with a history of uncomplicated or complicated peptic ulcers should be tested for H. pylori prior to beginning a NSAID or low dose aspirin. If present, H. pylori should be treated with appropriate therapy, even if it is believed that the prior ulcer was due to NSAIDs.


==References==
==References==
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[[Category:Gastroenterology]]
[[Category:Emergency medicine]]

Latest revision as of 22:02, 29 July 2020