Heart transplantation historical perspective: Difference between revisions

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The first human to human heart transplant was performed by Professor [[Christian Barnard]] at Groote Schuur Hospital, South Africa in December 1967. The patient was a Louis Washkansky of Cape Town, South Africa, who lived for 18 days after the procedure before dying of [[pneumonia]]. The donor was Denise Darvall, who was rendered [[Brain death|brain dead]] in a car accident. <ref name="pmid29968430">{{cite journal| author=Kim IC, Youn JC, Kobashigawa JA| title=The Past, Present and Future of Heart Transplantation. | journal=Korean Circ J | year= 2018 | volume= 48 | issue= 7 | pages= 565-590 | pmid=29968430 | doi=10.4070/kcj.2018.0189 | pmc=6031715 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29968430  }} </ref>
The first human to human heart transplant was performed by Professor [[Christian Barnard]] at Groote Schuur Hospital, South Africa in December 1967. The patient was a Louis Washkansky of Cape Town, South Africa, who lived for 18 days after the procedure before dying of [[pneumonia]]. The donor was Denise Darvall, who was rendered [[Brain death|brain dead]] in a car accident. <ref name="pmid29968430">{{cite journal| author=Kim IC, Youn JC, Kobashigawa JA| title=The Past, Present and Future of Heart Transplantation. | journal=Korean Circ J | year= 2018 | volume= 48 | issue= 7 | pages= 565-590 | pmid=29968430 | doi=10.4070/kcj.2018.0189 | pmc=6031715 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29968430  }} </ref>


The first successful United States heart transplant was done at St. Lukes hospital in Houston Texas by Denton Cooley, M. D. in June 1968. The donor was a teenage suicide victim (who had had an aortic coarctation repaired as a young child, also by Dr. Cooley) and the recipient, Mr. Thomas, had terminal severe [[cardiomyopathy]].  He survived 8 months before dying of rejection of the transplanted heart.  
*December 6, 1967- Adrian Kantrowitz performed the world's first pediatric heart transplant
*January 6, 1968- Norman Shumway performed the first adult human to human heart transplant in the United States at the Stanford University Hospital. <ref name="KalraSeth2016">{{cite journal|last1=Kalra|first1=Aakshi|last2=Seth|first2=Sandeep|last3=Hote|first3=MilindPadmaker|last4=Airan|first4=Balram|title=The story of heart transplantation: From cape town to cape comorin|journal=Journal of the Practice of Cardiovascular Sciences|volume=2|issue=2|year=2016|pages=120|issn=2395-5414|doi=10.4103/2395-5414.191525}}</ref>


A series of five subsequent heart transplants was done that month by Dr. Cooley followed by a number of transplants in Houston that year before the program was canceled leaving only Norman Shumway at Stanford University at San Francisco doing heart transplants and research on the rejection phenomenon.
Further developments in the field came in the form of:


1970 - Recipient selection criteria standardized
1970 - Recipient selection criteria standardized

Revision as of 09:37, 4 June 2020

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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D.; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [1]

Historical Perspective

The first heart transplanted into a human occurred in 1964 at the University of Mississippi Medical Center in Jackson, Mississippi when a team led by Dr. James Hardy transplanted a chimpanzee heart into a dying patient. [1]

The first human to human heart transplant was performed by Professor Christian Barnard at Groote Schuur Hospital, South Africa in December 1967. The patient was a Louis Washkansky of Cape Town, South Africa, who lived for 18 days after the procedure before dying of pneumonia. The donor was Denise Darvall, who was rendered brain dead in a car accident. [2]

  • December 6, 1967- Adrian Kantrowitz performed the world's first pediatric heart transplant
  • January 6, 1968- Norman Shumway performed the first adult human to human heart transplant in the United States at the Stanford University Hospital. [3]

Further developments in the field came in the form of:

1970 - Recipient selection criteria standardized

1973 - Surveillance endocardial biopsy

1977 - Distant donor heart procurement

1980 - Cyclosporine A

References

  1. Hardy, James D.; Chavez, Carlos M. (1968). "The first heart transplant in man". The American Journal of Cardiology. 22 (6): 772–781. doi:10.1016/0002-9149(68)90172-0. ISSN 0002-9149.
  2. Kim IC, Youn JC, Kobashigawa JA (2018). "The Past, Present and Future of Heart Transplantation". Korean Circ J. 48 (7): 565–590. doi:10.4070/kcj.2018.0189. PMC 6031715. PMID 29968430.
  3. Kalra, Aakshi; Seth, Sandeep; Hote, MilindPadmaker; Airan, Balram (2016). "The story of heart transplantation: From cape town to cape comorin". Journal of the Practice of Cardiovascular Sciences. 2 (2): 120. doi:10.4103/2395-5414.191525. ISSN 2395-5414.


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