Gonadoblastoma natural history, complications and prognosis: Difference between revisions

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{{CMG}}; {{AE}} {{Sahar}}
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==Overview==
==Overview==
Gonadoblastoma per se is a [[benign tumor]], however, it has the capacity to convert to [[dysgerminoma]] or other more [[malignant]] [[Germ cell tumor|germ cell tumors]] and produce [[steroids]] with resultant [[virilization]]. [[Prognosis]] is generally excellent after removing the [[tumor]].  
Gonadoblastoma per se is a [[benign tumor]], however, it has the capacity to convert to [[dysgerminoma]] or other more [[malignant]] [[Germ cell tumor|germ cell tumors]] and produce [[steroids]] with resultant [[virilization]]. [[Prognosis]] is generally excellent after removing the [[tumor]].
 
==Natural History, Complications, and Prognosis==
==Natural History, Complications, and Prognosis==
===Natural History===
===Natural History===
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*It is usually diagnosed during a workup for [[sex organ]] developmental disorders, [[primary amenorrhea]], and/or [[virilization]].   
*It is usually diagnosed during a workup for [[sex organ]] developmental disorders, [[primary amenorrhea]], and/or [[virilization]].   
===Complications===
===Complications===
*Common [[complications]] of gonadoblastoma include:ref name="978-1-4557-4858-7">{{cite book | last = Sperling | first = M | title = Pediatric endocrinology | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2014 | isbn = 978-1-4557-4858-7 }}</ref>
*Common [[complications]] of gonadoblastoma include:<ref name="978-1-4557-4858-7">{{cite book | last = Sperling | first = M | title = Pediatric endocrinology | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2014 | isbn = 978-1-4557-4858-7 }}</ref>
**[[Dysgerminoma]]
**[[Dysgerminoma]]
**[[Seminoma]]
**[[Seminoma]]
**Other gonadal [[malignancies]]
**Other gonadal [[malignancies]]
===Prognosis===
===Prognosis===
*[[Prognosis]] is generally excellent if the [[tumor]] is diagnosed and removed early.<ref name="urlPediatric Endocrinology | ScienceDirect">{{cite web |url=https://www.sciencedirect.com/book/9781455748587/pediatric-endocrinology |title=Pediatric Endocrinology &#124; ScienceDirect |format= |work= |accessdate=}}</ref>
*[[Prognosis]] is generally excellent if the [[tumor]] is diagnosed and removed early.<ref name="urlPediatric Endocrinology | ScienceDirect">{{cite web |url=https://www.sciencedirect.com/book/9781455748587/pediatric-endocrinology |title=Pediatric Endocrinology &#124; ScienceDirect |format= |work= |accessdate=}}</ref>
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[[Category:Medicine]]
[[Category:Medicine]]
[[Category:Primary care]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Up-To-Date]]
[[Category:Up-To-Date]]

Latest revision as of 21:54, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

Gonadoblastoma per se is a benign tumor, however, it has the capacity to convert to dysgerminoma or other more malignant germ cell tumors and produce steroids with resultant virilization. Prognosis is generally excellent after removing the tumor.

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

References

  1. 1.0 1.1 Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.
  2. Saia, Philip (2018). Clinical gynecologic oncology. Philadelphia, PA: Elsevier. ISBN 978-0-323-40067-1.
  3. "Pediatric Endocrinology | ScienceDirect".

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