Global aphasia: Difference between revisions

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* Impaired pronunciation of language and certain sounds.
* Impaired pronunciation of language and certain sounds.
* Poor control of mouth, voice box, and tongue.
* Poor control of mouth, voice box, and tongue.
==Risk Factors==


==Diagnosis==
==Diagnosis==

Revision as of 10:55, 20 January 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The symptoms of global aphasia are those of severe Broca's aphasia and Wernicke's aphasia combined. There is an almost total reduction of all aspects of spoken and written language, in expression as well as comprehension. Improvement may occur in one or both areas (expressive and receptive) over time with rehabilitation. What is interesting to point out is that in patients of global aphasia other cognitive skills remain functioning - a phenomenon affirming that language faculty is indeed a separate domain.

Global aphasia is a type of aphasia that is usually associated with a large lesion in the presylvian area. It involves a "left side blowout" which includes Broca's area, Wernicke's area and the Arcuate fasciculus.

When injury initially occurs to all of these areas, the progression starts out with Global aphasia in the first 1-2 days due brain swelling (Edema). From there it evolves into Brocas or Wernicke's aphasia for 1-3 months (usually Broca's), then it resolves into a presidual anomic aphasia. Studies show that spontaneous improvement, if it happens, occurs within six months, but complete recovery is rare.

Persons with global aphasia are usually mute or use repetitive vocalization. The person frequently uses simple words such as expletives. They are marked by a severe impairment of both understanding and expression of language. Although, they can maintain communication through gestures.

Pathophysiology

Like most forms of Aphasia, damage to the Broca's Area, in addition to Wernicke's Area is responsible for the combination of symptoms seen in Global Aphasia. Since both areas are involved in understanding and production of speech, a cluster of symptoms encompassing both will be present. Patient can barely comprehend or make sense out of spoken or written language.

Causes

Global Aphasia can generally be caused by stroke, cerebral tumors, cerebral infection, or certain long-standing cerebral conditions. However, stroke, seems to be the commonest cause of Global aphasia, and occurs alongside weakened limbs, which is usually an indication of other areas of the brain being involved. For this reason alone, Global Aphasia is generally more common in the elderly.

Symptoms

  • Impaired Comprehension and interpretation of language.
  • Impaired understanding and Formulation of language.
  • Paralysis of unilateral limbs(Stroke patients)
  • Impaired pronunciation of language and certain sounds.
  • Poor control of mouth, voice box, and tongue.

Diagnosis

A battery of tests are used to diagnose Global aphasia which includes:

MRI imaging.

CT scan imaging.

Language Assessment Tests

Prognosis

Treatment

Multiple treatment modalities exist for Global Aphasia which includes:

  • Repetitive Transcranial Magnetic Simulation(rTMS)
  • Speech and Language Therapy(SLT)



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