Glioblastoma multiforme MRI: Difference between revisions
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*Absent dual rim sign | *Absent dual rim sign | ||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" rowspan=3 |DWI/ADC | ||
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*Solid component | *Solid component | ||
:* Elevated signal on DWI is common in solid / enhancing component | |||
:* Diffusion restriction is typically intermediate similar to normal [[white matter]], but significantly elevated compared to surrounding vasogenic [[edema]] (which has facilitated diffusion) | |||
*ADC values correlate with grade: | |- | ||
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* ADC values correlate with grade: | |||
:* WHO IV (GBM) = 745 ± 135 x 10-6 mm2/s | |||
:* WHO III (anaplastic) = 1067 ± 276 x 10-6 mm2/s | |||
*Non-enhancing necrotic / cystic component | :* WHO II (low grade) = 1273 ± 293 x 10-6 mm2/s | ||
:* ADC threshold value of 1185 x 10-6 mm2/s sensitivity (97.6%) and specificity (53.1%) in the discrimination of high-grade (WHO grade III & IV) and low-grade (WHO grade II) gliomas | |||
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* Non-enhancing necrotic / cystic component | |||
:* Majority (>90%) have facilitated diffusion (ADC values > 1000 x 10-6 mm2/s) | |||
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Revision as of 14:27, 15 September 2015
Glioblastoma multiforme Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Glioblastoma multiforme MRI On the Web |
American Roentgen Ray Society Images of Glioblastoma multiforme MRI |
Risk calculators and risk factors for Glioblastoma multiforme MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
MRI
Brain MRI is helpful in the diagnosis of glioblastoma. On brain MRI, glioblastoma is characterized by:[1]
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DWI/ADC |
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Patient #1: Presented with increasing headaches
Patient #2
References
- ↑ XYZ of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma