Giant cell tumor of bone

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For patient information, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Osteoclastoma; giant cell myeloma; giant cell tumor

Overview

Historical Perspective

Pathophysiology

Giant cell tumor of bone occurs commonly in the distal femur, the proximal tibia, the distal radius and the sacrum.

Causes

Epidemiology and Demographics

Giant cell tumor of the bone accounts for 4-5% of primary bone tumors and 18.2% of benign bone tumors [1].

Age

  • It is more common in young adults between 20 and 40 years of age.

gender

  • It is more common in females with the rate of growth enhanced in pregnancy.

Risk Factors

Screening

Differentiating Giant cell tumor of bone from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Treatment

Medical Therapy

Surgery

References

Template:WikiDoc Sources

  1. Gamberi G, Serra M, Ragazzini P, Magagnoli G, Pazzaglia L, Ponticelli F, Ferrari C, Zanasi M, Bertoni F, Picci P, Benassi MS (2003). "Identification of markers of possible prognostic value in 57 giant cell tumors of bone". Oncology Reports. 10 (2): 351–6. PMID 12579271. Retrieved 2012-01-18.