Filariasis

Filariasis

Filariasis Microchapters
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Overview
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Differentiating Filariasis from other Diseases
Epidemiology and Demographics
Risk Factors
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Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
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Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Antimicrobial therapy

• Filariasis treatment

• 1. Lymphatic filariasis - Wuchereria bancrofti, Brugia malayi Brugia timori

• Preferred regimen: Diethylcarbamazine 6 mg/day PO qd for 12 days (single dose if patient will continue to live in endemic area or is younger than 9 years old) Template:With or without Albendazole 400 mg PO qd
• Alternative regimen: Doxycycline 200 mg/day for 4 weeks Template:With or without Ivermectin 150 μg/kg single dose (do not administer Ivermectin if there's a risk of serious adverse effects in areas where Loa loa is coendemic)
• Note: Do not administer Diethylcarbamazine where onchocerciasis is endemic due to the risk of causing severe local inflammation in patients with ocular microfilariae.

• 2. Cutaneous filariasis - Onchocercia volvulus, Loa loa

• Preferred regimen (1): Doxycycline 150 μg/kg single dose
• Preferred regimen (2): (Doxycycline 100 mg PO qd for 6 weeks OR 200 mg PO qd for 4 weeks) THEN Ivermectin after 4-6 months 150 μg/kg single dose
• Preferred regimen (3): Doxycycline 200 mg PO qd for 6 weeks THEN Ivermectin after 4-6 months 150 μg/kg single dose

Case Studies

Case #1 Template:Helminthiases

Template:WikiDoc Sources