Filariasis: Difference between revisions

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==[[Filariasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Filariasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
==Diagnosis==
[[Filariasis history and symptoms| History and Symptoms]] | [[Filariasis physical examination | Physical Examination]] | [[Filariasis laboratory findings|Laboratory Findings]] | [[Filariasis other diagnostic studies|Other Diagnostic Studies]]
[[Filariasis history and symptoms| History and Symptoms]] | [[Filariasis physical examination | Physical Examination]] | [[Filariasis laboratory findings|Laboratory Findings]] | [[Filariasis other diagnostic studies|Other Diagnostic Studies]]
Line 27: Line 28:
==Treatment==
==Treatment==
[[Filariasis medical therapy|Medical Therapy]] | [[Filariasis primary prevention|Primary Prevention]] | [[Filariasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Filariasis future or investigational therapies|Future or Investigational Therapies]]
[[Filariasis medical therapy|Medical Therapy]] | [[Filariasis primary prevention|Primary Prevention]] | [[Filariasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Filariasis future or investigational therapies|Future or Investigational Therapies]]
===Antimicrobial therapy===
:* '''Filariasis treatment'''
::* 1. '''Lymphatic filariasis - Wuchereria bancrofti, Brugia malayi Brugia timori'''<ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref><ref name="pmid22632644">{{cite journal| author=Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J| title=Nematode infections: filariases. | journal=Infect Dis Clin North Am | year= 2012 | volume= 26 | issue= 2 | pages= 359-81 | pmid=22632644 | doi=10.1016/j.idc.2012.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22632644  }} </ref>
:::* Preferred regimen: [[Diethylcarbamazine]] 6 mg/day PO qd for 12 days (single dose if patient will continue to live in endemic area or is younger than 9 years old) with or without [[Albendazole]] 400 mg PO qd
:::* Alternative regimen: [[Doxycycline]] 200 mg/day for 4 weeks with or without [[Ivermectin]] 150 μg/kg single dose (do not administer [[Ivermectin]] if there's a risk of serious adverse effects in areas where Loa loa is coendemic)
:::* Note: Do not administer [[Diethylcarbamazine]] where onchocerciasis is endemic due to the risk of causing severe local inflammation in patients with ocular microfilariae.
::* 2. '''Cutaneous filariasis - Onchocercia volvulus, Loa loa'''<ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref><ref name="pmid22632644">{{cite journal| author=Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J| title=Nematode infections: filariases. | journal=Infect Dis Clin North Am | year= 2012 | volume= 26 | issue= 2 | pages= 359-81 | pmid=22632644 | doi=10.1016/j.idc.2012.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22632644  }} </ref>
:::* Preferred regimen (1): [[Doxycycline]] 150 μg/kg single dose
:::* Preferred regimen (2): ([[Doxycycline]] 100 mg PO qd for 6 weeks {{or}} 200 mg PO qd for 4 weeks) {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose
:::* Preferred regimen (3): [[Doxycycline]] 200 mg PO qd for 6 weeks {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose


==Case Studies==
==Case Studies==
[[Filariasis case study one|Case #1]]
[[Filariasis case study one|Case #1]]
{{Helminthiases}}
{{Helminthiases}}
[[ar:فلاريا]]
[[de:Filariose]]
[[es:Filariasis]]
[[fr:Filariose]]
[[it:Filariosi]]
[[ms:Penyakit Untut]]
[[ja:フィラリア]]
[[nl:Filariasis]]
[[pt:Filaríase]]
[[sk:Vlásovce]]
[[wa:fiyaires]]


[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
[[Category:Neglected diseases]]
[[Category:Neglected diseases]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Disease]]
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{{WikiDoc Sources}}
==References==
{{reflist|2}}

Revision as of 23:50, 30 July 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Filariasis from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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