Fanconi anemia history and symptoms: Difference between revisions

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{{Fanconi anemia}}
{{Fanconi anemia}}


{{CMG}}
== Overview[edit | edit source] ==
The majority of patients with [disease name] are asymptomatic.


==Overview==
OR


==Symptoms==
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


===Hematological Abnormalities===
== History and Symptoms[edit | edit source] ==
Clinically, haematological abnormalities are the most serious symptoms in FA. By the age of 40, 98% of FA will have developed some type of haematologic abnormality. It is interesting to note however the few cases in which older patients have died without ever developing them.  
* The majority of patients with [disease name] are asymptomatic.
Symptoms appear progressively and often lead to complete [[bone marrow]] (BM) failure. While at birth blood count is usually normal, [[macrocytosis]]/[[megaloblastic anemia]], defined as unusually large red blood cells, is the first detected abnormality, often within the first decade of life (median age of onset is 7 years). Within the next 10 years, over 50% of patients presenting haematological abnormalities will have developed [[pancytopenia]], defined as abnormalities in two or more blood cell lineage. Indeed, [[thrombocytopenia]], defined as [[platelet]] count of less than 100x109/L precede [[neutropenia]], defined as a [[neutrophil]] count below 1x109/L, both appearing with relative equal frequencies, causing [[hemorrhage]] and increases in recurrent [[infections]].
OR
* The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
* Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
 
=== History[edit | edit source] ===
Patients with [disease name]] may have a positive history of:
* [History finding 1]
* [History finding 2]
* [History finding 3]
 
=== Common Symptoms[edit | edit source] ===
Common symptoms of [disease] include:
* [Symptom 1]
* [Symptom 2]
* [Symptom 3]
 
=== Less Common Symptoms[edit | edit source] ===
Less common symptoms of [disease name] include
* [Symptom 1]
* [Symptom 2]
* [Symptom 3]


==References==
==References==

Revision as of 19:06, 16 June 2018

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Overview[edit | edit source]

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms[edit | edit source]

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History[edit | edit source]

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms[edit | edit source]

Common symptoms of [disease] include:

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

Less Common Symptoms[edit | edit source]

Less common symptoms of [disease name] include

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

References