Familial amyloidosis history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Common [[symptoms]] of familial amyloidosis include [[abdominal pain]], [[edema]] and [[enlarged tongue]]. Less common [[symptoms]] of amyloidosis include [[Gastrointestinal bleeding|gastrointestinal bleeding, gross]] [[hematuria]], [[hoarseness]] and [[paresthesias]]. | |||
===History=== | ===History=== | ||
Patients with | Patients with amyloidosis may have a positive history of:<ref name="pmid24497558">{{cite journal |vauthors=Mahmood S, Palladini G, Sanchorawala V, Wechalekar A |title=Update on treatment of light chain amyloidosis |journal=Haematologica |volume=99 |issue=2 |pages=209–21 |date=February 2014 |pmid=24497558 |pmc=3912950 |doi=10.3324/haematol.2013.087619 |url=}}</ref> | ||
*[ | *[[Dyspnea]] | ||
*[ | *[[Lethargy]] | ||
*[ | *[[Weight loss]] | ||
*[[Chest discomfort]] | |||
*[[Fevers]] or [[chills]] | |||
*[[Night sweats]] | |||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of [ | Common [[symptoms]] of familial amyloidosis include:<ref name="pmid26161016">{{cite journal |vauthors=Lim AY, Lee JH, Jung KS, Gwag HB, Kim DH, Kim SJ, Lee GY, Kim JS, Kim HJ, Lee SY, Lee JE, Jeon ES, Kim K |title=Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience |journal=Korean J. Intern. Med. |volume=30 |issue=4 |pages=496–505 |date=July 2015 |pmid=26161016 |pmc=4497337 |doi=10.3904/kjim.2015.30.4.496 |url=}}</ref><ref name="pmid23227278">{{cite journal |vauthors=Baker KR, Rice L |title=The amyloidoses: clinical features, diagnosis and treatment |journal=Methodist Debakey Cardiovasc J |volume=8 |issue=3 |pages=3–7 |date=2012 |pmid=23227278 |pmc=3487569 |doi= |url=}}</ref> | ||
*[ | * [[Fatigue]] | ||
*[ | * [[Weight loss]] | ||
*[ | * [[Edema]] | ||
*[[Abdominal pain]] | |||
*[[Enlarged tongue]] | |||
*Skin and nail changes | |||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of [ | Less common [[symptoms]] of familial amyloidosis include:<ref name="pmid10228037">{{cite journal |vauthors=Hamidi Asl K, Liepnieks JJ, Nakamura M, Benson MD |title=Organ-specific (localized) synthesis of Ig light chain amyloid |journal=J. Immunol. |volume=162 |issue=9 |pages=5556–60 |date=May 1999 |pmid=10228037 |doi= |url=}}</ref> | ||
*[ | *[[Hoarseness]] | ||
*[ | *[[Gastrointestinal bleeding]] | ||
*[ | *[[Diarrhea]] | ||
*Paresthesias | |||
*Gross [[hematuria]] | |||
*Irritative [[urinary symptoms]] | |||
==References== | ==References== |
Revision as of 16:59, 30 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
Common symptoms of familial amyloidosis include abdominal pain, edema and enlarged tongue. Less common symptoms of amyloidosis include gastrointestinal bleeding, gross hematuria, hoarseness and paresthesias.
History
Patients with amyloidosis may have a positive history of:[1]
Common Symptoms
Common symptoms of familial amyloidosis include:[2][3]
- Fatigue
- Weight loss
- Edema
- Abdominal pain
- Enlarged tongue
- Skin and nail changes
Less Common Symptoms
Less common symptoms of familial amyloidosis include:[4]
- Hoarseness
- Gastrointestinal bleeding
- Diarrhea
- Paresthesias
- Gross hematuria
- Irritative urinary symptoms
References
- ↑ Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.
- ↑ Lim AY, Lee JH, Jung KS, Gwag HB, Kim DH, Kim SJ, Lee GY, Kim JS, Kim HJ, Lee SY, Lee JE, Jeon ES, Kim K (July 2015). "Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience". Korean J. Intern. Med. 30 (4): 496–505. doi:10.3904/kjim.2015.30.4.496. PMC 4497337. PMID 26161016.
- ↑ Baker KR, Rice L (2012). "The amyloidoses: clinical features, diagnosis and treatment". Methodist Debakey Cardiovasc J. 8 (3): 3–7. PMC 3487569. PMID 23227278.
- ↑ Hamidi Asl K, Liepnieks JJ, Nakamura M, Benson MD (May 1999). "Organ-specific (localized) synthesis of Ig light chain amyloid". J. Immunol. 162 (9): 5556–60. PMID 10228037.