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The incidence of esthesioneuroblastoma is approximately 0.4 per 100,000 individuals worldwide. Esthesioneuroblastoma can present in a wide range of age groups; however, it is mostly noted in a bimodal distribution, occurring most frequently in the second and sixth decades of life. There is no racial predilection to the esthesioneuroblastoma.<ref name="ShirzadiDrazin2013">{{cite journal|last1=Shirzadi|first1=Ali S.|last2=Drazin|first2=Doniel G.|last3=Strickland|first3=Allison S.|last4=Bannykh|first4=Serguei I.|last5=Johnson|first5=J. Patrick|title=Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup|journal=Case Reports in Surgery|volume=2013|year=2013|pages=1–8|issn=2090-6900|doi=10.1155/2013/107315}}</ref><ref name="radio"> Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016</ref>
The incidence of esthesioneuroblastoma is approximately 0.4 per 100,000 individuals worldwide. Esthesioneuroblastoma can present in a wide range of age groups; however, it is mostly noted in a bimodal distribution, occurring most frequently in the second and sixth decades of life. There is no racial predilection to the esthesioneuroblastoma.<ref name="ShirzadiDrazin2013">{{cite journal|last1=Shirzadi|first1=Ali S.|last2=Drazin|first2=Doniel G.|last3=Strickland|first3=Allison S.|last4=Bannykh|first4=Serguei I.|last5=Johnson|first5=J. Patrick|title=Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup|journal=Case Reports in Surgery|volume=2013|year=2013|pages=1–8|issn=2090-6900|doi=10.1155/2013/107315}}</ref><ref name="radio"> Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016</ref>
==Epidemiology and Demographics==
==Epidemiology and Demographics==
Esthesioneuroblastoma is noted in 4 out of 10 million individuals, accounting for 5% of sinonasal and 3% of intracranial tumors.<ref name="ShirzadiDrazin2013">{{cite journal|last1=Shirzadi|first1=Ali S.|last2=Drazin|first2=Doniel G.|last3=Strickland|first3=Allison S.|last4=Bannykh|first4=Serguei I.|last5=Johnson|first5=J. Patrick|title=Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup|journal=Case Reports in Surgery|volume=2013|year=2013|pages=1–8|issn=2090-6900|doi=10.1155/2013/107315}}</ref> Approximately 1,000 cases have been identified since Berger and Luc described the first case in 1924.<ref name="pmid9252701">{{cite journal| author=Broich G, Pagliari A, Ottaviani F| title=Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924. | journal=Anticancer Res | year= 1997 | volume= 17 | issue= 4A | pages= 2683-706 | pmid=9252701 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9252701  }} </ref> According to the BBC, only 201 cases of the disease have been recorded worldwide in the past two decades. A 1997 literature search identified 1,457 cases in the published literature since its discovery in 1924, however 487 were cited in more than one paper, bringing the total of reported cases to 945.  
Esthesioneuroblastoma is noted in 4 out of 10 million individuals, accounting for 5% of sinonasal and 3% of intracranial tumors.<ref name="ShirzadiDrazin2013">{{cite journal|last1=Shirzadi|first1=Ali S.|last2=Drazin|first2=Doniel G.|last3=Strickland|first3=Allison S.|last4=Bannykh|first4=Serguei I.|last5=Johnson|first5=J. Patrick|title=Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup|journal=Case Reports in Surgery|volume=2013|year=2013|pages=1–8|issn=2090-6900|doi=10.1155/2013/107315}}</ref> Approximately 1,000 cases have been identified since Berger and Luc described the first case in 1924.<ref name="pmid9252701">{{cite journal| author=Broich G, Pagliari A, Ottaviani F| title=Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924. | journal=Anticancer Res | year= 1997 | volume= 17 | issue= 4A | pages= 2683-706 | pmid=9252701 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9252701  }} </ref> According to the BBC, only 201 cases of the disease have been recorded worldwide in the past two decades. A 1997 literature search identified 1,457 cases in the published literature since its discovery in 1924, however 487 were cited in more than one paper, bringing the total of reported cases to 945.<ref name="wiki"> Esthesioneuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Esthesioneuroblastoma Accessed on January 26, 2016</ref >
 
==Incidence==
==Incidence==
The incidence of esthesioneuroblastoma was estimated to be 0.4 cases per 100,000 individuals worldwide.  
The incidence of esthesioneuroblastoma was estimated to be 0.4 cases per 100,000 individuals worldwide.  

Revision as of 20:35, 26 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

The incidence of esthesioneuroblastoma is approximately 0.4 per 100,000 individuals worldwide. Esthesioneuroblastoma can present in a wide range of age groups; however, it is mostly noted in a bimodal distribution, occurring most frequently in the second and sixth decades of life. There is no racial predilection to the esthesioneuroblastoma.[1][2]

Epidemiology and Demographics

Esthesioneuroblastoma is noted in 4 out of 10 million individuals, accounting for 5% of sinonasal and 3% of intracranial tumors.[1] Approximately 1,000 cases have been identified since Berger and Luc described the first case in 1924.[3] According to the BBC, only 201 cases of the disease have been recorded worldwide in the past two decades. A 1997 literature search identified 1,457 cases in the published literature since its discovery in 1924, however 487 were cited in more than one paper, bringing the total of reported cases to 945.[4]

Incidence

The incidence of esthesioneuroblastoma was estimated to be 0.4 cases per 100,000 individuals worldwide.

Age

Esthesioneuroblastoma commonly affects individuals in a wide range of age groups younger than 90/older than 3 (3-90) years of age. There exists a bimodal peak of occurrence in the third and sixth decades of life. The majority of cases of esthesioneuroblastoma occur in patients between 40 and 70 years of age; the median age at diagnosis is 53 years.It can present in a wide range of age groups; however, it is mostly noted in a bimodal distribution, occurring most frequently in the second and sixth decades of life.

Race

There is no racial predilection to the esthesioneuroblastoma.

Gender

There was a moderate male predominance with a 55:45 male:female ratio. Males are more commonly affected with esthesioneuroblastoma than females. The male to female ratio is approximately [1.2 > 1] to 1.[5][6][7][8]

References

  1. 1.0 1.1 Shirzadi, Ali S.; Drazin, Doniel G.; Strickland, Allison S.; Bannykh, Serguei I.; Johnson, J. Patrick (2013). "Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup". Case Reports in Surgery. 2013: 1–8. doi:10.1155/2013/107315. ISSN 2090-6900.
  2. Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016
  3. Broich G, Pagliari A, Ottaviani F (1997). "Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924". Anticancer Res. 17 (4A): 2683–706. PMID 9252701.
  4. Esthesioneuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Esthesioneuroblastoma Accessed on January 26, 2016
  5. Ward PD, Heth JA, Thompson BG, Marentette LJ (2009). "Esthesioneuroblastoma: Results and Outcomes of a Single Institution's Experience". Skull Base. 19 (2): 133–40. doi:10.1055/s-0028-1096195. PMC 2671304. PMID 19721769.
  6. Diaz EM, Johnigan RH, Pero C, El-Naggar AK, Roberts DB, Barker JL; et al. (2005). "Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center". Head Neck. 27 (2): 138–49. doi:10.1002/hed.20127. PMID 15654688.
  7. Resto VA, Eisele DW, Forastiere A, Zahurak M, Lee DJ, Westra WH (2000). "Esthesioneuroblastoma: the Johns Hopkins experience". Head Neck. 22 (6): 550–8. PMID 10941155.
  8. Bachar G, Goldstein DP, Shah M, Tandon A, Ringash J, Pond G; et al. (2008). "Esthesioneuroblastoma: The Princess Margaret Hospital experience". Head Neck. 30 (12): 1607–14. doi:10.1002/hed.20920. PMID 18798301.

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