Esophageal candidiasis natural history, complications and prognosis: Difference between revisions

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==Overview==
==Overview==
Candida esophagitis is very responsive to antifungal therapy. Complications can be systemic due to the spread of infection to the blood stream or local as esophageal stricture and obstruction.
Candida esophagitis is very responsive to [[Antifungal|antifungal therapy]]. Complications can be systemic due to the spread of infection to the [[blood stream]] or local as [[esophageal stricture]] and obstruction.


==Natural history==
==Natural history==
Esophageal candidiasis is usually responsive to antifungal treatment with complete resolution. However, recurrence and other complications are frequently encountered due to associated immunosuppression.
If left untreated, complications as [[esophageal stricture]] and candidaemia ensue.


==Complications==
==Complications==
Complications can be systemic due to spread of [[candida]] or localized due to the local invasion of the [[fungus]].<ref name="pmid3181663">{{cite journal |vauthors=Naito Y, Yoshikawa T, Oyamada H, Tainaka K, Morita Y, Kogawa T, Sugino S, Kondo M |title=Esophageal candidiasis |journal=Gastroenterol. Jpn. |volume=23 |issue=4 |pages=363–70 |year=1988 |pmid=3181663 |doi= |url=}}</ref>
*Systemic spread and fungemia
*Systemic spread and fungemia
*Esophageal perforation
*[[Esophageal perforation]]
*Tracheoesophageal fistula
*[[Tracheoesophageal fistula]]
*Esophageal stricture
*[[Esophageal stricture]]
*Esophageal obstruction
*Esophageal obstruction


==Prognosis==
==Prognosis==
*Prognosis is excellent unless candidaemia and shock occur.  
*Prognosis is excellent and Esophageal candidiaisis is usually responsive to [[Antifungal drug|antifungal treatment]].
*Recurrence is common after treatment due to persistence of the predisposing [[immunosuppression]].  


==References==
==References==

Latest revision as of 15:03, 1 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Candida esophagitis is very responsive to antifungal therapy. Complications can be systemic due to the spread of infection to the blood stream or local as esophageal stricture and obstruction.

Natural history

If left untreated, complications as esophageal stricture and candidaemia ensue.

Complications

Complications can be systemic due to spread of candida or localized due to the local invasion of the fungus.[1]

Prognosis

  • Prognosis is excellent and Esophageal candidiaisis is usually responsive to antifungal treatment.
  • Recurrence is common after treatment due to persistence of the predisposing immunosuppression.

References

  1. Naito Y, Yoshikawa T, Oyamada H, Tainaka K, Morita Y, Kogawa T, Sugino S, Kondo M (1988). "Esophageal candidiasis". Gastroenterol. Jpn. 23 (4): 363–70. PMID 3181663.