Eisenmenger’s syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD [2]

Overview

Eisenmenger's syndrome is causes by cardiac defects that shunt blood heading to the systemic circulation back into the pulmonary circulation. These defects include ventricular septal defect, atrial septal defect, atrioventricular canal defect, patent ductus arteriosus, and truncus arteriosus.

Causes

Eisenmenger's syndrome is caused by a defect in the heart, which allows oxygenated blood to flow back into the pulmonary circulation, instead of going out to the systemic circulation. Cardiac defects that can lead to Eisenmenger's syndrome include ^[1]^[2]^[3]:

Common Causes

Less Common Causes

Unrepaired Tetralogy of Fallot
Patent ductus arteriosus
Surgical systemic-to-pulmonary anastomosis

References

↑ WOOD P (1958). "The Eisenmenger syndrome or pulmonary hypertension with reversed central shunt". Br Med J. 2 (5099): 755–62. doi:10.1136/bmj.2.5099.755. PMC 2026272. PMID 13572894.
↑ Nwosu NI, Omejua E, Udora N, Nwosu E (2017). "Secundum atrial septal defect with Eisenmenger syndrome: A scarcely reported disease in Nigeria". Niger Med J. 58 (2): 81–83. doi:10.4103/0300-1652.219346. PMC 5726179. PMID 29269987.
↑ Kaemmerer H, Mebus S, Schulze-Neick I, Eicken A, Trindade PT, Hager A et al. (2010) The adult patient with eisenmenger syndrome: a medical update after dana point part I: epidemiology, clinical aspects and diagnostic options. Curr Cardiol Rev 6 (4):343-55. DOI:10.2174/157340310793566154 PMID: 22043211

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[pmid13572894-1] WOOD P (1958). "The Eisenmenger syndrome or pulmonary hypertension with reversed central shunt". Br Med J. 2 (5099): 755–62. doi:10.1136/bmj.2.5099.755. PMC 2026272. PMID 13572894.

[pmid29269987-2] Nwosu NI, Omejua E, Udora N, Nwosu E (2017). "Secundum atrial septal defect with Eisenmenger syndrome: A scarcely reported disease in Nigeria". Niger Med J. 58 (2): 81–83. doi:10.4103/0300-1652.219346. PMC 5726179. PMID 29269987.

[pmid22043211-3] Kaemmerer H, Mebus S, Schulze-Neick I, Eicken A, Trindade PT, Hager A et al. (2010) The adult patient with eisenmenger syndrome: a medical update after dana point part I: epidemiology, clinical aspects and diagnostic options. Curr Cardiol Rev 6 (4):343-55. DOI:10.2174/157340310793566154 PMID: 22043211

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