Cryptogenic cirrhosis
For patient information, click Cryptogenic Cirrhosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Imam Ali Shah, MBBS [2]
Synonyms and keywords: Idiopathic Cirrhosis
Overview
Cryptogenic cirrhosis is defined as cirrhosis of unknown origin. It is a diagnosis of exclusion and is only made after extensive investigative workup when the underlying cause of cirrhosis remains elusive. The cause of this condition is, by definition, unknown; however, there are correlations suggesting that metabolic dysfunction-associated steatohepatitis (MASH) plays a significant role . Advances in investigative methods, understanding of liver disease, and acknowledgment of metabolic dysfunction-associated steatohepatitis (MASH) as a plausible cause have led to a signifcant decrease in the use of this term.
Historical Perspective
Pathophysiology
Genetics
Associated Conditions
Gross Pathology
Microscopic Pathology
Causes
Differentiating Cryptogenic Cirrhosis from other Diseases
Epidemiology and Demographics
Age
Gender
Race
Developed Countries
Developing Countries
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
If available, the diagnostic criteria are provided here.
History
A directed history should be obtained to ascertain
Symptoms
"Type symptom here" is pathognomonic of the "type disease name here".
"Type non specific symptoms" may be present.
Past Medical History
Family History
Social History
Occupational
Alcohol
The frequency and amount of alcohol consumption should be characterized.