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===Incidence===
===Incidence===
*The incidence of otesochondromas is approximately 30,000 per 100,000 of all cartilage tumors and 2,000 per 100,000 of all bone tumors.
*The incidence of otesochondromas is approximately 30,000 per 100,000 of all cartilage tumors and 2,000 per 100,000 of all bone tumors.<ref name="pmid22147000">{{cite journal |vauthors=Verdegaal SH, Bovée JV, Pansuriya TC, Grimer RJ, Ozger H, Jutte PC, San Julian M, Biau DJ, van der Geest IC, Leithner A, Streitbürger A, Klenke FM, Gouin FG, Campanacci DA, Marec-Berard P, Hogendoorn PC, Brand R, Taminiau AH |title=Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients |journal=Oncologist |volume=16 |issue=12 |pages=1771–9 |date=2011 |pmid=22147000 |pmc=3248776 |doi=10.1634/theoncologist.2011-0200 |url=}}</ref>


===Prevalence===
===Prevalence===
*The prevalence of benign cartilage tumors is approximately 27000 per 100,000 individuals of all bone tumors and 70,000 per 100,000 of all cartilage tumors.
*The prevalence of benign cartilage tumors is approximately 27000 per 100,000 individuals of all bone tumors and 70,000 per 100,000 of all cartilage tumors.<ref name="pmid25994192">{{cite journal |vauthors=Stomp W, Reijnierse M, Kloppenburg M, de Mutsert R, Bovée JV, den Heijer M, Bloem JL |title=Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee |journal=Eur Radiol |volume=25 |issue=12 |pages=3480–7 |date=December 2015 |pmid=25994192 |pmc=4636526 |doi=10.1007/s00330-015-3764-6 |url=}}</ref>
*The prevalence of enchondromas is approximately 12,000-24,000 per 100,000 individuals of benign bone tumors and 3000-10,000 of all bone tumors.
*The prevalence of enchondromas is approximately 12,000-24,000 per 100,000 individuals of benign bone tumors and 3000-10,000 of all bone tumors.<ref name="pmid26919862">{{cite journal |vauthors=McCarthy C, Anderson WJ, Vlychou M, Inagaki Y, Whitwell D, Gibbons CL, Athanasou NA |title=Primary synovial chondromatosis: a reassessment of malignant potential in 155 cases |journal=Skeletal Radiol. |volume=45 |issue=6 |pages=755–62 |date=June 2016 |pmid=26919862 |doi=10.1007/s00256-016-2353-3 |url=}}</ref>
*The prevalence of periostal chondromas is approximately 1000 per 100,000 individuals of all chondromas and 100 per 100,000 of all bone tumors.
*The prevalence of periostal chondromas is approximately 1000 per 100,000 individuals of all chondromas and 100 per 100,000 of all bone tumors.


===Age===
===Age===
*Patients of all age groups may develop enchondromas.
*Patients of all age groups may develop enchondromas.
*The incidence of enchondroma peaks in the third and fourth decades of life.
*The incidence of enchondroma peaks in the third and fourth decades of life.<ref name="pmid20453254">{{cite journal |vauthors=Matysiakiewicz J, Tomasik P, Miszczyk L, Spindel J, Widuchowski J, Koczy B, Chrobok A, Mrozek T |title=Manifestations, diagnosis and surgical treatment of enchondroma--own experience |journal=Ortop Traumatol Rehabil |volume=12 |issue=2 |pages=155–9 |date=2010 |pmid=20453254 |doi= |url=}}</ref>
*Periosteal chondromas are frequently diagnosed in the second or third decades of life.
*Periosteal chondromas are frequently diagnosed in the second or third decades of life.
*Patients of all age groups may develop synovial chondromas, and fifth decade is a peak incidence.
*Patients of all age groups may develop synovial chondromas, and fifth decade is a peak incidence.<ref name="pmid11061692">{{cite journal |vauthors=Flemming DJ, Murphey MD |title=Enchondroma and chondrosarcoma |journal=Semin Musculoskelet Radiol |volume=4 |issue=1 |pages=59–71 |date=2000 |pmid=11061692 |doi= |url=}}</ref>


===Race===
===Race===
Line 27: Line 27:
===Gender===
===Gender===
*Enchondroma affects men and women equally.
*Enchondroma affects men and women equally.
*Males are more commonly affected by periosteal chondromas than females.  
*Males are more commonly affected by periosteal chondromas than females.<ref name="pmid26024560">{{cite journal |vauthors=Chun KA, Stephanie S, Choi JY, Nam JH, Suh JS |title=Enchondroma of the Foot |journal=J Foot Ankle Surg |volume=54 |issue=5 |pages=836–9 |date=2015 |pmid=26024560 |doi=10.1053/j.jfas.2015.01.002 |url=}}</ref>
*Male are more commonly affected by osteochondromas than female. The male to female ratio is approximately 1.8 to 1.  
*Male are more commonly affected by osteochondromas than female. The male to female ratio is approximately 1.8 to 1.<ref name="pmid26024560">{{cite journal |vauthors=Chun KA, Stephanie S, Choi JY, Nam JH, Suh JS |title=Enchondroma of the Foot |journal=J Foot Ankle Surg |volume=54 |issue=5 |pages=836–9 |date=2015 |pmid=26024560 |doi=10.1053/j.jfas.2015.01.002 |url=}}</ref>
*Male are more commonly affected by synovial chondroma than female.The male to female ratio is approximately 2 to 1.
*Male are more commonly affected by synovial chondroma than female.The male to female ratio is approximately 2 to 1.<ref name="pmid24891585">{{cite journal |vauthors=Goedhart LM, Ploegmakers JJ, Kroon HM, Zwartkruis EC, Jutte PC |title=The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands |journal=Bone Joint J |volume=96-B |issue=6 |pages=823–8 |date=June 2014 |pmid=24891585 |doi=10.1302/0301-620X.96B6.33037 |url=}}</ref>


==References==
==References==

Revision as of 16:30, 25 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Farima Kahe M.D. [2] Soujanya Thummathati, MBBS [3]

Overview

Epidemiology and Demographics

Incidence

  • The incidence of otesochondromas is approximately 30,000 per 100,000 of all cartilage tumors and 2,000 per 100,000 of all bone tumors.[1]

Prevalence

  • The prevalence of benign cartilage tumors is approximately 27000 per 100,000 individuals of all bone tumors and 70,000 per 100,000 of all cartilage tumors.[2]
  • The prevalence of enchondromas is approximately 12,000-24,000 per 100,000 individuals of benign bone tumors and 3000-10,000 of all bone tumors.[3]
  • The prevalence of periostal chondromas is approximately 1000 per 100,000 individuals of all chondromas and 100 per 100,000 of all bone tumors.

Age

  • Patients of all age groups may develop enchondromas.
  • The incidence of enchondroma peaks in the third and fourth decades of life.[4]
  • Periosteal chondromas are frequently diagnosed in the second or third decades of life.
  • Patients of all age groups may develop synovial chondromas, and fifth decade is a peak incidence.[5]

Race

  • There is no racial predilection to chondroma.

Gender

  • Enchondroma affects men and women equally.
  • Males are more commonly affected by periosteal chondromas than females.[6]
  • Male are more commonly affected by osteochondromas than female. The male to female ratio is approximately 1.8 to 1.[6]
  • Male are more commonly affected by synovial chondroma than female.The male to female ratio is approximately 2 to 1.[7]

References

  1. Verdegaal SH, Bovée JV, Pansuriya TC, Grimer RJ, Ozger H, Jutte PC, San Julian M, Biau DJ, van der Geest IC, Leithner A, Streitbürger A, Klenke FM, Gouin FG, Campanacci DA, Marec-Berard P, Hogendoorn PC, Brand R, Taminiau AH (2011). "Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients". Oncologist. 16 (12): 1771–9. doi:10.1634/theoncologist.2011-0200. PMC 3248776. PMID 22147000.
  2. Stomp W, Reijnierse M, Kloppenburg M, de Mutsert R, Bovée JV, den Heijer M, Bloem JL (December 2015). "Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee". Eur Radiol. 25 (12): 3480–7. doi:10.1007/s00330-015-3764-6. PMC 4636526. PMID 25994192.
  3. McCarthy C, Anderson WJ, Vlychou M, Inagaki Y, Whitwell D, Gibbons CL, Athanasou NA (June 2016). "Primary synovial chondromatosis: a reassessment of malignant potential in 155 cases". Skeletal Radiol. 45 (6): 755–62. doi:10.1007/s00256-016-2353-3. PMID 26919862.
  4. Matysiakiewicz J, Tomasik P, Miszczyk L, Spindel J, Widuchowski J, Koczy B, Chrobok A, Mrozek T (2010). "Manifestations, diagnosis and surgical treatment of enchondroma--own experience". Ortop Traumatol Rehabil. 12 (2): 155–9. PMID 20453254.
  5. Flemming DJ, Murphey MD (2000). "Enchondroma and chondrosarcoma". Semin Musculoskelet Radiol. 4 (1): 59–71. PMID 11061692.
  6. 6.0 6.1 Chun KA, Stephanie S, Choi JY, Nam JH, Suh JS (2015). "Enchondroma of the Foot". J Foot Ankle Surg. 54 (5): 836–9. doi:10.1053/j.jfas.2015.01.002. PMID 26024560.
  7. Goedhart LM, Ploegmakers JJ, Kroon HM, Zwartkruis EC, Jutte PC (June 2014). "The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands". Bone Joint J. 96-B (6): 823–8. doi:10.1302/0301-620X.96B6.33037. PMID 24891585.


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