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==Diagnostic criteria==
==Diagnostic criteria==
An algorithm  for diagnosis of cholangitis:<ref name="Lee2009">{{cite journal|last1=Lee|first1=John G.|title=Diagnosis and management of acute cholangitis|journal=Nature Reviews Gastroenterology & Hepatology|volume=6|issue=9|year=2009|pages=533–541|issn=1759-5045|doi=10.1038/nrgastro.2009.126}}</ref><ref name="KiriyamaTakada2013">{{cite journal|last1=Kiriyama|first1=Seiki|last2=Takada|first2=Tadahiro|last3=Strasberg|first3=Steven M.|last4=Solomkin|first4=Joseph S.|last5=Mayumi|first5=Toshihiko|last6=Pitt|first6=Henry A.|last7=Gouma|first7=Dirk J.|last8=Garden|first8=O. James|last9=Büchler|first9=Markus W.|last10=Yokoe|first10=Masamichi|last11=Kimura|first11=Yasutoshi|last12=Tsuyuguchi|first12=Toshio|last13=Itoi|first13=Takao|last14=Yoshida|first14=Masahiro|last15=Miura|first15=Fumihiko|last16=Yamashita|first16=Yuichi|last17=Okamoto|first17=Kohji|last18=Gabata|first18=Toshifumi|last19=Hata|first19=Jiro|last20=Higuchi|first20=Ryota|last21=Windsor|first21=John A.|last22=Bornman|first22=Philippus C.|last23=Fan|first23=Sheung-Tat|last24=Singh|first24=Harijt|last25=de Santibanes|first25=Eduardo|last26=Gomi|first26=Harumi|last27=Kusachi|first27=Shinya|last28=Murata|first28=Atsuhiko|last29=Chen|first29=Xiao-Ping|last30=Jagannath|first30=Palepu|last31=Lee|first31=Sung Gyu|last32=Padbury|first32=Robert|last33=Chen|first33=Miin-Fu|last34=Dervenis|first34=Christos|last35=Chan|first35=Angus C.W.|last36=Supe|first36=Avinash N.|last37=Liau|first37=Kui-Hin|last38=Kim|first38=Myung-Hwan|last39=Kim|first39=Sun-Whe|title=TG13 guidelines for diagnosis and severity grading of acute cholangitis (with videos)|journal=Journal of Hepato-Biliary-Pancreatic Sciences|volume=20|issue=1|year=2013|pages=24–34|issn=18686974|doi=10.1007/s00534-012-0561-3}}</ref>


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Revision as of 17:33, 14 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

Diagnostic criteria

An algorithm for diagnosis of cholangitis:[1][2]


 
 
 
 
 
 
 
 
 
Diagnosis of
acute cholangitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Definitive diagnosis

Signs of infection and pus finding in bile during:
ERCP
PTCA
•Surgery
 
 
 
 
 
Charcot triad
Fever
Jaundice
Abdominal pain

Reynold's pentad (includes 2 extra features)
Sepsis
Mental confusion
 
 
 
 
Tokyo guidelines 2013(TG 13)

A.Systemic inflammation
A-1. Fever and/or shaking chills
A-2. Laboratory data: evidence of inflammatory response

B.Cholestasis
B-1. Jaundice
B-2. Laboratory data: abnormal liver function tests

C.Imaging
C-1. Biliary dilatation
C-2. Evidence of the etiology on imaging (stricture, stone, stent etc.)

Suspected diagnosis: One item in A + one item in either B or C
Definite diagnosis: One item in A, one item in B and one item in C
Note: ERCP= Endoscopic retrograde cholangiopancreatography, PTCA =Percutaneous transhepatic cholangiography
A-2: Abnormal white blood cell counts, increase of serum C-reactive protein levels, and other changes indicating inflammation
B-2: Increased serum ALP, cGTP (GGT), AST and ALT levels.

References

  1. Lee, John G. (2009). "Diagnosis and management of acute cholangitis". Nature Reviews Gastroenterology & Hepatology. 6 (9): 533–541. doi:10.1038/nrgastro.2009.126. ISSN 1759-5045.
  2. Kiriyama, Seiki; Takada, Tadahiro; Strasberg, Steven M.; Solomkin, Joseph S.; Mayumi, Toshihiko; Pitt, Henry A.; Gouma, Dirk J.; Garden, O. James; Büchler, Markus W.; Yokoe, Masamichi; Kimura, Yasutoshi; Tsuyuguchi, Toshio; Itoi, Takao; Yoshida, Masahiro; Miura, Fumihiko; Yamashita, Yuichi; Okamoto, Kohji; Gabata, Toshifumi; Hata, Jiro; Higuchi, Ryota; Windsor, John A.; Bornman, Philippus C.; Fan, Sheung-Tat; Singh, Harijt; de Santibanes, Eduardo; Gomi, Harumi; Kusachi, Shinya; Murata, Atsuhiko; Chen, Xiao-Ping; Jagannath, Palepu; Lee, Sung Gyu; Padbury, Robert; Chen, Miin-Fu; Dervenis, Christos; Chan, Angus C.W.; Supe, Avinash N.; Liau, Kui-Hin; Kim, Myung-Hwan; Kim, Sun-Whe (2013). "TG13 guidelines for diagnosis and severity grading of acute cholangitis (with videos)". Journal of Hepato-Biliary-Pancreatic Sciences. 20 (1): 24–34. doi:10.1007/s00534-012-0561-3. ISSN 1868-6974.