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  Image = Trypanosoma cruzi crithidia.jpeg |
  Image = Trypanosoma cruzi crithidia.jpeg |
  Caption = Photomicrograph of [[Giemsa]]-stained ''Trypanosoma cruzi'' [[crithidia]] ([[Centers for Disease Control and Prevention|CDC]]) |
  Caption = Photomicrograph of [[Giemsa]]-stained ''Trypanosoma cruzi'' [[crithidia]] ([[Centers for Disease Control and Prevention|CDC]]) |
DiseasesDB = 13415 |
ICD10 = {{ICD10|B|57||b|50}} |
ICD9 = {{ICD9|086}} |
ICDO = |
OMIM = |
MedlinePlus = 001372 |
MeshID = D014355 |
}}
}}
{{Chagas disease}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{Chagas disease}}
{{CMG}}; {{AE}} {{YD}}, {{Hudakarman}} {{RT}}, {{Tamar}}
{{CMG}}
 
{{SK}} Chagas' disease; American trypanosomiasis; Trypanosoma cruzi infection


==[[Chagas disease overview|Overview]]==
==[[Chagas disease overview|Overview]]==


==[[Chagas disease historical perspective|Historical Perspective]]==
==[[Chagas disease historical perspective|Historical Perspective]]==
==[[Chagas disease classification|Classification]]==


==[[Chagas disease pathophysiology|Pathophysiology]]==
==[[Chagas disease pathophysiology|Pathophysiology]]==
Line 28: Line 26:
==[[Chagas disease differentiating chagas disease from other diseases|Differentiating Chagas disease from other Diseases]]==
==[[Chagas disease differentiating chagas disease from other diseases|Differentiating Chagas disease from other Diseases]]==


==[[Chagas disease epidemiology and demographics|Epidemiology & Demographics]]==
==[[Chagas disease epidemiology and demographics|Epidemiology and Demographics]]==


==[[Chagas disease risk factors|Risk Factors]]==
==[[Chagas disease risk factors|Risk Factors]]==


==[[Chagas disease screening|Screening]]==
=[[Chagas disease screening|Screening]]==
 
==[[Chagas disease natural history|Complications & Prognosis]]==


==Diagnosis==
==[[Chagas disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
[[Chagas disease history and symptoms|History and Symptoms]] | [[Chagas disease physical examination|Physical Examination]] | [[Chagas disease staging|Staging]] | [[Chagas disease laboratory findings|Laboratory Findings]] | [[Chagas disease electrocardiogram|Electrocardiogram]] | [[Chagas disease other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==[[Diagnosis]]==
[[Chagas disease medical therapy|Medical Therapy]] | [[Chagas disease surgery|Surgery]] | [[Chagas disease primary prevention|Primary prevention]] | [[Chagas disease secondary prevention|Secondary prevention]] | [[Chagas disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Chagas disease future or investigational therapies|Future or Investigational Therapies]]
==See also==
*[[Tropical disease]]
*[[Drugs for Neglected Diseases Initiative]]
* Distinguish from: [[Chaga mushroom]]


==References==
[[Chagas disease diagnostic criteria|Diagnostic Criteria]] | [[Chagas disease history and symptoms|History and Symptoms]] | [[Chagas disease physical examination | Physical Examination]] | [[Chagas disease laboratory findings | Laboratory findings]] | [[Chagas disease electrocardiogram | Electrocardiogram]] | [[Chagas disease x ray|X-ray]] | [[Chagas disease electrocardiogram | Electrocardiogram]] | [[Chagas disease  echocardiography and ultrasound|Echocardiography and Ultrasound]] |[[Chagas disease CT scan | CT scan]] | [[Chagas disease MRI | MRI]] | [[Chagas disease other imaging findings|Other Imaging Findings]] | [[Chagas disease other diagnostic studies|Other diagnostic studies]]
* CDC, Division of Parasitic Diseases. [http://www.cdc.gov/NCIDOD/DPD/PARASITES/chagasdisease/factsht_chagas_disease.htm Chagas Disease Fact Sheet.] (23 September 2004). Accessed 24 September 2006.
* {{cite journal | author=Dumonteil E, Escobedo-Ortegon J, Reyes-Rodriguez N, Arjona-Torres A, Ramirez-Sierra M | title=Immunotherapy of Trypanosoma cruzi infection with DNA vaccines in mice. | journal=Infect Immun | volume=72 | issue=1 | pages=46–53 | year=2004 | id=PMID 14688079}}
* CDC, Division of Parasitic Diseases.[http://www.cdc.gov/ncidod/dpd/parasites/chagasdisease/disease_chagas_disease.htm Chagas Disease](23 October 2007). Accessed 16 August 2007.
* CDC, Division of Parasitic Diseases.[http://www.cdc.gov/ncidod/dpd/parasites/chagasdisease/epidemiology_chagas_disease.htm Chagas Disease Epidemiology.](23 October 2007). Accessed 16 August 2007.
*CDC, Division of Parasitic Diseases. [http://www.cdc.gov/ncidod/dpd/parasites/chagasdisease/treatment_chagas_disease.htm Treatment](23 October 2007). Accessed 16 August 2007.


==Further reading==
==[[Treatment]]==
<div class="references-small">
* {{cite journal | author=Coutinho M | title=Ninety years of Chagas disease: a success story at the periphery. | journal=Soc Stud Sci | volume=29 | issue=4 | pages=519-49 | year=1999 | id=PMID 11623933}}
* {{cite journal | author=Dias J, Silveira A, Schofield C | title=The impact of Chagas disease control in Latin America: a review. | journal=Mem Inst Oswaldo Cruz | volume=97 | issue=5 | pages=603-12 | year=2002 | id=PMID 12219120 | url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000500002&tlng=es&lng=en&nrm=iso}}
* {{cite journal | author=Kropf S, Azevedo N, Ferreira L | title=Biomedical research and public health in Brazil: the case of Chagas' disease (1909–50). | journal=Soc Hist Med | volume=16 | issue=1 | pages=111-29 | year=2003 | id=PMID 14598820}}
* {{cite journal | year = 1999 | title = International Symposium to commemorate the 90th anniversary of the discovery of Chagas disease (Rio de Janeiro, April 11–16, 1999) | journal = Memorias do Instituto Oswaldo Cruz | volume = 94 | issue = Suppl. I | url =http://www.dbbm.fiocruz.br/tropical/chagas/memmain.html}}
* {{cite journal | author=Moncayo A | title=Progress towards interruption of transmission of Chagas disease. | journal=Mem Inst Oswaldo Cruz | volume=94 Suppl 1 | pages=401-4 | id=PMID 10677765 | url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700079&lng=en&nrm=iso}}
* {{cite journal | author=Prata A | title=Evolution of the clinical and epidemiological knowledge about Chagas disease 90 years after its discovery. | journal=Mem Inst Oswaldo Cruz | volume=94 Suppl 1 | pages=81-8 | id=PMID 10677694 | url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700008&lng=en&nrm=iso}}
* {{cite journal | author=Franco-Paredes C | title=Chagas disease: an impediment in achieving the Millennium Development Goals in Latin America. | journal=BMC International Health and Human Rights | volume=7 | pages=7 | year=2007 | id=PMID 17725836 | url=http://http://www.biomedcentral.com/1472-698X/7/7/abstract}}
* {{cite book | editor = Kevin M. Tyler & Michael A. Miles | title = World Class Parasites. Volume 7: American Trypanosomiasis | publisher = Kluwer Academic Publishers | id = ISBN 1-4020-7323-2}} [http://www.amazon.com/dp/1402073232/ Amazon review]
</div>


==External links==
[[Chagas disease medical therapy|Medical Therapy]] | [[Chagas disease surgery|Surgery]] | [[Chagas disease primary prevention|Primary Prevention]] | [[Chagas disease secondary prevention|Secondary Prevention]] | [[Chagas disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Chagas disease future or investigational therapies|Future or Investigational Therapies]]
* [http://www.vcu.edu/csbc/vpp/ VCU Virtual Parasite Project]
* [http://www.allaboutchagasdisease.com''All About Chagas Disease''], Chagas' disease Information & Prevention, Identification, also in Spanish.
* [http://chagaspace.org/eng/index.htm ''Chagaspace''], also in Spanish.
* [http://www.unibio.unam.mx/chagmex ChagMex: Database on-line]. UNAM-Instituto de Biología.
* [http://www.paho.org/english/ad/dpc/cd/chagas.htm Chagas Disease]. PanAmerican Health Organization.
* [http://www.phac-aspc.gc.ca/tmp-pmv/info/am_trypan_e.html Disease Information. American Trypanosomiasis or Chagas' Disease]. Travel Medicine Program. Health Canada.
* [http://www.lib.uiowa.edu/hardin/md/trypanosomiasisAmer.html Links to Chagas' Disease pictures (Hardin MD/Univ of Iowa)]
* [http://www.uta.edu/chagas Link to "The Kiss of Death"]. An anthropological view of Chagas' disease (Joseph Bastien/Univ of Texas at Arlington).


===Recent news and events===
==Case Studies==
* [http://www.pe.com/localnews/rivcounty/stories/PE_News_Local_S_blood18.3d5c374.html/ Chagas' disease parasite found in desert blood samples]
[[Chagas disease case study one|Case #1]]
* ''Chagas Control in the Southern Cone Countries: History of an International Initiative, 1991/2001'', PAHO. ([http://www.paho.org/English/AD/DPC/CD/dch-historia-incosur.htm Full text e-book])
* [http://cruzi.unsam.edu.ar/ Genome Sequencing Project]
* [http://news.bbc.co.uk/2/hi/health/4681707.stm Parasites' genetic code 'cracked'] From BBC
*Catholic Relief Services. [http://www.crs.org/our_work/where_we_work/overseas/latin_america_and_the_caribbean/bolivia/improvement.cfm Housing Improvement and Chagas' Disease Prevention Project]
*2006: [http://www.nature.com/nature/journal/v440/n7081/full/440153a.html Nature.com / Scott M. Landfear: ''Flagella are whip-like structures that power the movement of certain cells. Analysis of a single-cell parasite, the African trypanosome, reveals that flagella are also essential for viability in this organism.''] (restricted commercial access now)
*[http://www.sciencemag.org/cgi/search?fulltext=chagas&collection_num=MEDICINE&collections_search_keyword_go.x=0&collections_search_keyword_go.y=0 Science Magazine Search Results: ''Chagas'']


{{Protozoal diseases}}
{{Protozoal diseases}}
{{Link FA|pl}}
[[ar:شاجاس]]
[[ca:Malaltia de Chagas]]
[[de:Chagas-Krankheit]]
[[es:Enfermedad de Chagas]]
[[fr:Maladie de Chagas]]
[[it:Malattia di Chagas]]
[[lt:Čagaso liga]]
[[ms:Penyakit Cagas]]
[[nl:Ziekte van Chagas]]
[[ja:シャーガス病]]
[[pt:Doença de Chagas]]
[[sv:Chagas sjukdom]]
[[pl:Choroba Chagasa]]


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Latest revision as of 23:25, 15 October 2020

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Chagas disease
Photomicrograph of Giemsa-stained Trypanosoma cruzi crithidia (CDC)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D., Huda A. Karman, M.D. Raviteja Guddeti, M.B.B.S. [2], Tamar Sifri [3]

Synonyms and keywords: Chagas' disease; American trypanosomiasis; Trypanosoma cruzi infection

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Chagas disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening=

Natural History, Complications and Prognosis

Diagnosis

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