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{{Cervical cancer}}
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==Overview==
==Overview==
Cervical cancer is one of the most common and fatal forms of cancer worldwide.  Worldwide, cervical cancer is the fifth most deadly cancer in women.<ref>[http://www.who.int/mediacentre/factsheets/fs297/en/index.html]</ref> It affects about 1 per 123 women per year and kills about 9 per 100,000 per year.  In the United States, it is only the 8th most common cancer of women. In 1998, about 12,800 women were diagnosed in the US and about 4,800 died. Among gynecological cancers it ranks behind [[endometrial cancer]] and [[ovarian cancer]]. The incidence and mortality in the United States are about half those for the rest of the world, which is due in part to the success of screening with the [[Pap smear]].<ref>[http://www.aafp.org/afp/20000301/1369.html]</ref>  In the United States, the age-adjusted [[prevalence]] of cervical cancer is 87.9 per 100,000 in 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
According to the Centers for disease control and prevention ([[CDC]]) , [[cancer]] is the second leading cause of death in the United States after heart disease. One of every four deaths in the United States is due to cancer. Cervical cancer once was one of leading cause of mortality and cancer related death in women worldwide and in US, over the past 50 years, regular [[Pap smear]] screening caused significant drop in [[incidence]] and [[mortality rate]] of cervical cancer. Cervical neoplasia still is very common in developing countries, studies shown there is an association between age and socoeconomic status of women and [[incidence]] of [[infection]] with [[human papilloma virus]].  


==Epidemiology and Demographics==
==Epidemiology and demographics==
===Prevalence===
* According to Centers for disease control and prevention ([[CDC]]) , [[cancer]] is the second leading cause of death in the United States after heart disease. One of every four deaths in the United States is due to cancer. <ref name="urlCDC - Data Visualizations Tool Technical Notes - NPCR - Cancer">{{cite web |url=https://www.cdc.gov/cancer/uscs/technical_notes/index.htm?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcancer%2Fnpcr%2Fuscs%2Ftechnical_notes%2Findex.htm |title=CDC - Data Visualizations Tool Technical Notes - NPCR - Cancer |format= |work= |accessdate=}}</ref>
 
* Cervical cancer once was one of leading cause of [[mortality]] and cancer related death in women worldwide and in US, over the past 50 years, regular [[Pap smear]] screening caused significant drop in incidence and [[mortality rate]] of cervical cancer. In terms of frequency, it is ranked 14th now in the US but still is very common in least developed countries. <ref name="urlUSCS Data Visualizations">{{cite web |url=https://gis.cdc.gov/Cancer/USCS/DataViz.html |title=USCS Data Visualizations |format= |work= |accessdate=}}</ref>  
* In the United States, the age-adjusted [[prevalence]] of cervical cancer is 87.9 per 100,000 in 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* In the United States, cervical cancer is more common among Hispanics, African-Americans, Asians and pascific islanders, and followed by whites. Native Alaskans and Indians have the lowest rate. Age of diagnosis is usually above 30 years old, in their midlife. Number of new cases of cervical cancer was 7.4 per 100,000 women per year and number of deaths was 2.3 per 100,000 women per year based on statistical datas collected on 2015. <ref name="pmid11314432" />
 
* According to the [[American Cancer Society]], estimates for cervical cancer in the United States for 2018 are: About 13,240 new cases of invasive cervical cancer will be diagnosed and about 4,170 women will die from cervical cancer. Based on recent [[CDC]] datas, States with highest rates of cervical cancers are Arkansas(10.4%), Louisiana(9.8%), Alabama(9.4%), Kentucky(9.4%), Texas(9.1%), Mississippi(9.1%), Kansas(9.0%), D.C(8.9%), Florida(8.7%), Nevada(8.7%).<ref name="pmid11314432">{{cite journal |vauthors=Franco EL, Duarte-Franco E, Ferenczy A |title=Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection |journal=CMAJ |volume=164 |issue=7 |pages=1017–25 |date=April 2001 |pmid=11314432 |pmc=80931 |doi= |url=}}</ref>
===Incidence===
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{{Cervical cancer}}
* The delay-adjusted [[incidence]] of cervical cancer in 2011 was estimated to be 6.83 per 100,000 persons in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
* In 2011, the age-adjusted [[incidence]] of cervical cancer was 6.73 per 100,000 persons in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
*In Great Britain, the incidence is 8.8/100,000 per year (2001), similar to the rest of Northern Europe, and mortality is 2.8/100,000 per year (2003) (Cancer Research UK Cervical cancer statistics for the UK). With a 42% reduction from 1988-1997 the National Health Service (NHS) implemented screening programme has been highly successful, screening the highest risk age group (25-49 years) every 3 years, and those ages 50-64 every 5 years.  In 2011, 3,064 women in the United Kingdom were diagnosed with cervical cancer.<ref name=uk>[http://www.cancerresearchuk.org/cancer-info/cancerstats/types/cervix/ Cancer Research UK]</ref>
 
===Age===
 
* While the overall age-adjusted [[incidence]] of cervical cancer in the United States between 2007 and 2011 is 7.8 per 100,000, the age-adjusted [[incidence]] of cervical cancer by age category is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** Under 65 years: 7.3 per 100,000
** 65 and over: 11.5 per 100,000
 
===Race===
 
* Shown below is a table depicting the age-adjusted [[prevalence]] of cervical cancer by race in 2011 in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
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| style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''Age-adjusted [[prevalence]]'''|| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |87.9 per 100,000||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |91.3 per 100,000||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |81.9 per 100,000||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left | 75.5 per 100,000||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |141 per 100,000
|}
 
* Shown below is an image depicting the [[incidence]] of cervical cancer in the white and black races in the United States between 1975 and 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
[[Image:Incidence of cervical cancer in white vs black in USA.PNG|The incidence of cervical cancer in the white and black races in the United States between 1975 and 2011]]
 
* Shown below is an image depicting the [[incidence]] of cervical cancer by race in the United States between 1975 and 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
[[Image:Incidence of cervical cancer by race in USA.PNG|The incidence of cervical cancer by race in the United States between 1975 and 2011]]
 
<small> API: Asian/Pacific Islander; AI/AN: American Indian/ Alaska Native</small>
 
===Percent Distribution of Cervical Cancer by Histology===
Among patients with histologically confirmed cases of cervical cancer, the percent distribution of the types of the disease between 2007 and 2011 in the United States are:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* [[Carcinoma]]: 98.1%
** [[Epidermoid carcinoma]]: 66.1%
*** [[Squamous cell carcinoma]]: 45.2%
*** Squamous cell, keratinizing: 7.1%
*** Squamous cell, non keratinizing: 8.9%
*** Squamous cell, microinvasive: 3.3%
***Other: 1.5%
** [[Adenocarcinoma]]: 27,7%
*** [[Adenocarcinoma]] no otherwise specified: 14.5%
*** Adenosquamous: 3.7%
*** Other adenocarcinoma: 9.5%
** Other specific carcinoma: 1.5%
** Unspecified carcinoma: 2.9%
* [[Sarcoma]]: 0.4%
* Other specific types: 1%
* Unspecified: 0.6%


==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}


[[Category:Disease]]
[[Category:Disease]]
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:primary care]]
[[Category:Medicine]]
 
{{WH}}
{{WS}}

Latest revision as of 20:51, 29 July 2020

Cervical cancer Microchapters

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Overview

Historical Perspective

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Diagnosis

Diagnostic Study of Choice

History and Symptoms

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Chest X Ray

CT

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Directions to Hospitals Treating Cervical cancer

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

According to the Centers for disease control and prevention (CDC) , cancer is the second leading cause of death in the United States after heart disease. One of every four deaths in the United States is due to cancer. Cervical cancer once was one of leading cause of mortality and cancer related death in women worldwide and in US, over the past 50 years, regular Pap smear screening caused significant drop in incidence and mortality rate of cervical cancer. Cervical neoplasia still is very common in developing countries, studies shown there is an association between age and socoeconomic status of women and incidence of infection with human papilloma virus.

Epidemiology and demographics

  • According to Centers for disease control and prevention (CDC) , cancer is the second leading cause of death in the United States after heart disease. One of every four deaths in the United States is due to cancer. [1]
  • Cervical cancer once was one of leading cause of mortality and cancer related death in women worldwide and in US, over the past 50 years, regular Pap smear screening caused significant drop in incidence and mortality rate of cervical cancer. In terms of frequency, it is ranked 14th now in the US but still is very common in least developed countries. [2]
  • In the United States, cervical cancer is more common among Hispanics, African-Americans, Asians and pascific islanders, and followed by whites. Native Alaskans and Indians have the lowest rate. Age of diagnosis is usually above 30 years old, in their midlife. Number of new cases of cervical cancer was 7.4 per 100,000 women per year and number of deaths was 2.3 per 100,000 women per year based on statistical datas collected on 2015. [3]
  • According to the American Cancer Society, estimates for cervical cancer in the United States for 2018 are: About 13,240 new cases of invasive cervical cancer will be diagnosed and about 4,170 women will die from cervical cancer. Based on recent CDC datas, States with highest rates of cervical cancers are Arkansas(10.4%), Louisiana(9.8%), Alabama(9.4%), Kentucky(9.4%), Texas(9.1%), Mississippi(9.1%), Kansas(9.0%), D.C(8.9%), Florida(8.7%), Nevada(8.7%).[3]

Cervical cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cervical Cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cervical Cancer During Pregnancy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cervical cancer epidemiology and demographics On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Cervical cancer epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Cervical cancer epidemiology and demographics

CDC on Cervical cancer epidemiology and demographics

Cervical cancer epidemiology and demographics in the news

Blogs on Cervical cancer epidemiology and demographics

Directions to Hospitals Treating Cervical cancer

Risk calculators and risk factors for Cervical cancer epidemiology and demographics

References

  1. "CDC - Data Visualizations Tool Technical Notes - NPCR - Cancer".
  2. "USCS Data Visualizations".
  3. 3.0 3.1 Franco EL, Duarte-Franco E, Ferenczy A (April 2001). "Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection". CMAJ. 164 (7): 1017–25. PMC 80931. PMID 11314432.

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