Cefradine

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Cefradine
Clinical data
Routes of
administration
Oral, IM, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityWell absorbed
Protein binding<10%
MetabolismNil
Elimination half-life0.9 hours
ExcretionRenal, unchanged
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC16H19N3O4S
Molar mass349.406 g/mol

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Overview

Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic.

Indications

It has similar spectrum of activity to cefalexin.

Dosage

Dosage by mouth for adults is 250–500 mg every 6 hours, or 500 mg to 1 g every 12 hours. In severe infections up to 1 g every 6 hours may be used. Dosages for children are based upon their weight with 25–50 mg/kg total daily dose given in 2–4 divided doses.

Formulations

Caspules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

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