Candida vulvovaginitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

The diagnosis of Candida vulvovaginitis is based on the clinical findings, supported by laboratory findings. Laboratory studies done for diagnosis include measurement of the vaginal pH, visualization of hyphae on wet mount/ microscopy, as well as culture.

Laboratory Findings

The following laboratory tests are done in the diagnosis of Candida vulvovaginitis:[1][2][3]

  • Vaginal pH: in Candida vulvovaginitis, vaginal pH is normal (ranges from 4.0-4.5)
  • Microscopy/ wet mount: visualizes Candida hyphae or spores
  • Culture: culture for diagnosing Candida vulvovaginitis is not routinely done. However, it should be done in a symptomatic woman with a negative microscopy and a normal vaginal pH. Sabouraud agar, Nickerson's medium or Microstix-candida culture media may be used

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References

  1. Eckert LO (2006). "Clinical practice. Acute vulvovaginitis". N. Engl. J. Med. 355 (12): 1244–52. doi:10.1056/NEJMcp053720. PMID 16990387.
  2. Mendling W, Brasch J (2012). "Guideline vulvovaginal candidosis (2010) of the German Society for Gynecology and Obstetrics, the Working Group for Infections and Infectimmunology in Gynecology and Obstetrics, the German Society of Dermatology, the Board of German Dermatologists and the German Speaking Mycological Society". Mycoses. 55 Suppl 3: 1–13. doi:10.1111/j.1439-0507.2012.02185.x. PMID 22519657.
  3. Sobel JD (2007). "Vulvovaginal candidosis". Lancet. 369 (9577): 1961–71. doi:10.1016/S0140-6736(07)60917-9. PMID 17560449.
  4. "Public Health Image Library (PHIL)".


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