Calciphylaxis surgery: Difference between revisions

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==Overview==
The optimal treatment is prevention. Rigorous and continuous control of phosphate and calcium balance most probably will avoid the metabolic changes which may lead to calciphylaxis. There is no specific treatment. Of the treatments that exist, none is internationally recognised as the standard of care.
 
==Surgery==
An acceptable surgical treatment could include:
 
*Urgent parathyroidectomy: The efficacy of this measure remains uncertain although calciphylaxis is associated with frank hyperparathyroidism. Urgent parathyroidectomy may benefit those patients who have uncontrollable plasma calcium and phosphorus concentrations despite dialysis. Also, [[cinacalcet]] can be used and may serve as an alternative to parathyroidectomy. The trade name of [[cinacalcet]] is [[Sensipar]] or [[Mimpara]].
*Patients who receive [[kidney transplant]]s also receive [[immunosuppression]]. Considering lowering the dose of or discontinuing the use of immunosuppressive drugs in renal transplant patients who continue to have persistent or progressive calciphylactic skin lesions can contribute to an acceptable treatment of calciphylaxis.
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs content]]


[[Category:Disease]]
[[Category:Disease]]

Latest revision as of 15:42, 28 September 2012

Calciphylaxis Microchapters

Home

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Calciphylaxis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Biopsy

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Calciphylaxis surgery On the Web

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Ongoing Trials at Clinical Trials.gov

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NICE Guidance

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Blogs on Calciphylaxis surgery

Directions to Hospitals Treating Calciphylaxis

Risk calculators and risk factors for Calciphylaxis surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The optimal treatment is prevention. Rigorous and continuous control of phosphate and calcium balance most probably will avoid the metabolic changes which may lead to calciphylaxis. There is no specific treatment. Of the treatments that exist, none is internationally recognised as the standard of care.

Surgery

An acceptable surgical treatment could include:

  • Urgent parathyroidectomy: The efficacy of this measure remains uncertain although calciphylaxis is associated with frank hyperparathyroidism. Urgent parathyroidectomy may benefit those patients who have uncontrollable plasma calcium and phosphorus concentrations despite dialysis. Also, cinacalcet can be used and may serve as an alternative to parathyroidectomy. The trade name of cinacalcet is Sensipar or Mimpara.
  • Patients who receive kidney transplants also receive immunosuppression. Considering lowering the dose of or discontinuing the use of immunosuppressive drugs in renal transplant patients who continue to have persistent or progressive calciphylactic skin lesions can contribute to an acceptable treatment of calciphylaxis.

References


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