Bleeding diathesis: Difference between revisions

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{{Bleeding diathesis}}
{{Bleeding diathesis}}
{{CMG}}; {{MJ}}
{{CMG}}; {{MJ}}
== Overview ==
== Classification ==
== Differential Diagnosis ==
{| class="wikitable"
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| rowspan="8" |Platelet disorders
| rowspan="7" |Thrombocytopenia
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==== Infection-Induced Thrombocytopenia ====
<span name="harr_c115s002s001s002p001"></span><span name="9100754"></span>
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==== Drug-Induced Thrombocytopenia ====
<span name="harr_c115s002s001s003p001"></span><span name="9100757"></span>
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==== Heparin-Induced Thrombocytopenia ====
<span name="harr_c115s002s001s004p001"></span><span name="9100761"></span>
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==== Immune Thrombocytopenic Purpura (ITP) ====
<span name="harr_c115s002s001s005p001"></span><span name="9100771"></span>
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|-
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==== Inherited Thrombocytopenia ====
<span name="harr_c115s002s001s006p001"></span><span name="9100783"></span>
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==== Thrombotic Thrombocytopenic Purpura (TTP) ====
<span name="harr_c115s002s002s001p001"></span><span name="9100787"></span>
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==== Hemolytic Uremic Syndrome ====
<span name="harr_c115s002s002s002p001"></span><span name="9100796"></span>
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=== Thromobcytosis ===
<span name="harr_c115s002s003p001"></span><span name="9100800"></span>
|Thrombocytosis in response to acute or chronic inflammation has not been associated with an increased thrombotic risk. In fact, patients with markedly elevated platelet counts (>1.5 million), usually seen in the setting of a myeloproliferative disorder, have an increased risk of bleeding. This appears to be due, at least in part, to acquired von Willebrand disease (VWD) due to platelet-VWF adhesion and removal.
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==== Qualitative Disorders of Platelet Function ====
<span name="harr_c115s002s004s001p001"></span><span name="9100803"></span>
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==== Inherited Disorders of Platelet Function ====
<span name="harr_c115s002s004s001p001"></span><span name="9100803"></span>
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==== Acquired Disorders of Platelet Function ====
<span name="harr_c115s002s004s002p001"></span><span name="9100808"></span>
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=== von Willebrand Disease ===
<span name="harr_c115s002s005p001"></span><span name="9100810"></span>
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| rowspan="2" |Vessel wall disorders
|Metabolic and Inflammatory Disorders
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|Inherited Disorders of the Vessel Wall
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| rowspan="12" |Coagulation disorders
|Fibrinogen
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|Prothrombin
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| rowspan="1" |Factor V
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| rowspan="1" |Factor VII
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| rowspan="1" |Factor VIII
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| rowspan="1" |Factor IX
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| rowspan="1" |Factor X
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| rowspan="1" |Factor XI
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| rowspan="1" |Factor XII
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|HK
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| rowspan="1" |Prekallikrein
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| rowspan="1" |Factor XIII
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| rowspan="3" |[[Hemophilia]]
|Type A
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|Type B
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|Type C
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| rowspan="4" |Rare diseases
|Disseminated Intravascular Coagulation
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|Vitamin K Deficiency
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|Coagulation Disorders Associated with Liver Failure
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|Acquired Inhibitors of Coagulation Factors
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|}

Revision as of 16:54, 6 August 2018


Bleeding diathesis main page

Overview

Classification

Differential Diagnosis

Platelet disorders
Immune Thrombocytopenic Purpura
Thrombotic Thrombocytopenic Purpura
Hemolytic Uremic Syndrome
Thrombocytosis
Von Willebrand Disease
Coagulation disorders
Fibrinogen deficiency
Prothrombin deficiency
Factor V deficiency
Factor VII deficiency
Factor VIII deficiency
Factor IX deficiency
Factor X deficiency
Factor XI deficiency
Factor XII deficiency
High-molecular-weight kininogen deficiency
Prekallikrein deficiency
Factor XIII deficiency
Hemophilia
Rare diseases
Disseminated Intravascular Coagulation
Vitamin K Deficiency

Different types of Von-Willebrand diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Mehrian Jafarizade, M.D [2]

Overview

Classification

Differential Diagnosis

Platelet disorders Thrombocytopenia

Infection-Induced Thrombocytopenia

Drug-Induced Thrombocytopenia

Heparin-Induced Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)

Inherited Thrombocytopenia

Thrombotic Thrombocytopenic Purpura (TTP)

Hemolytic Uremic Syndrome

Thromobcytosis

Thrombocytosis in response to acute or chronic inflammation has not been associated with an increased thrombotic risk. In fact, patients with markedly elevated platelet counts (>1.5 million), usually seen in the setting of a myeloproliferative disorder, have an increased risk of bleeding. This appears to be due, at least in part, to acquired von Willebrand disease (VWD) due to platelet-VWF adhesion and removal.

Qualitative Disorders of Platelet Function

Inherited Disorders of Platelet Function

Acquired Disorders of Platelet Function

von Willebrand Disease

Vessel wall disorders Metabolic and Inflammatory Disorders
Inherited Disorders of the Vessel Wall
Coagulation disorders Fibrinogen
Prothrombin
Factor V
Factor VII
Factor VIII
Factor IX
Factor X
Factor XI
Factor XII
HK
Prekallikrein
Factor XIII
Hemophilia Type A
Type B
Type C
Rare diseases Disseminated Intravascular Coagulation
Vitamin K Deficiency
Coagulation Disorders Associated with Liver Failure
Acquired Inhibitors of Coagulation Factors