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==Causes==
==Causes==
Many cases are likely due to [[Herpes Simplex Virus]] (HSV) reactivation
Many cases are likely due to [[Herpes Simplex Virus]] (HSV) reactivation
===Infectious Causes===
*[[Herpes simplex virus]] activation is the most likely cause of Bell's Palsy.
*[[Herpes Zoster]] may be the second most common viral infection. 
*[[Cytomegalovirus]]
*[[Epstein Barr virus]]
*[[Adenovirus]]
*[[Rubella]] virus
*[[Mumps]]
*[[Influenza B]]
*[[Coxsackie]] virus 
*Rickettsial infection
*[[Ehrlichiosis]]
*Borrelia burdopheri
*[[HIV]]
===Non-Infectious Causes===


'''Infectious causes '''
*Several cases of Bell' Palsy were linked to an inactivated intranasal influenza vaccine in Switzerland  
 
*Genetic predisposition may be likely   
:*[[Herpes simplex virus]] activation is the most likely cause of Bell's Palsy.
*[[Ischemia]] of the facial nerve  
:*[[Herpes Zoster]] may be the second most common viral infection. 
*Tumors and compression of the facial nerve
:*[[Cytomegalovirus]]
*Temporal bone fracture
:*[[Epstein Barr virus]]
*Systemic Lupus Erythematosus ([[SLE]])
:*[[Adenovirus]]
*[[Sarcoidosis]]
:*[[Rubella]] virus
:*[[Mumps]]
:*[[Influenza B]]
:*[[Coxsackie]] virus 
:*Rickettsial infection
:*[[Ehrlichiosis]]
:*Borrelia burdopheri
:*[[HIV]]
 
'''Non-infectious causes'''
 
:*Several cases of Bell' Palsy were linked to an inactivated intranasal influenza vaccine in Switzerland  
:*Genetic predisposition may be likely   
:*[[Ischemia]] of the facial nerve  
:*Tumors and compression of the facial nerve
:*Temporal bone fracture
:*Systemic Lupus Erythematosus ([[SLE]])
:*[[Sarcoidosis]]
 
===Lyme Disease===
===Lyme Disease===
 
*Facial nerve palsy is the most common cranial [[neuropathy]] associated with Lyme meningitis.  
:*Facial nerve palsy is the most common cranial [[neuropathy]] associated with Lyme meningitis.  
*Screening for antibodies to B.burgdorferi  not recommended among patients with seventh nerve palsy with no additional manifestations of Lyme disease.
:*Screening for antibodies to B.burgdorferi  not recommended among patients with seventh nerve palsy with no additional manifestations of Lyme disease.
*Findings suggestive of possible [[Lyme disease]] include the development of facial palsy in a young patient, heart block, arthritis, vertigo, and hearing loss.
:*Findings suggestive of possible [[Lyme disease]] include the development of facial palsy in a young patient, heart block, arthritis, vertigo, and hearing loss.
 
===HIV===
===HIV===
 
*HIV infection rarely causes facial palsy.
:*HIV infection rarely causes facial palsy.
*Onset at the time of sero-conversion when a [[CSF]] lymphocytosis is usually present.  
:*Onset at the time of sero-conversion when a [[CSF]] lymphocytosis is usually present.  
*In the later stages when cellular immunity wanes, the facial palsy is typically due to another infection such as Zoster, chronic demyelinating polyradiculopathy, or meningeal [[lymphomatosis]].
:*In the later stages when cellular immunity wanes, the facial palsy is typically due to another infection such as Zoster, chronic demyelinating polyradiculopathy, or meningeal [[lymphomatosis]].
 
===Melkersson-Rosenthal Syndrome===
===Melkersson-Rosenthal Syndrome===
 
*Facial paralysis, episodic facial swelling, and a fissured tongue, typically beginning in adolescence, with recurrent episodes of facial palsy.  
:*Facial paralysis, episodic facial swelling, and a fissured tongue, typically beginning in adolescence, with recurrent episodes of facial palsy.  
*Incomplete forms of this syndrome outnumber those with the classic triad.  
:*Incomplete forms of this syndrome outnumber those with the classic triad.  
*The cause is unknown, and treatment unproven.
:*The cause is unknown, and treatment unproven.
 
===Other Entities===
===Other Entities===
 
*Bacterial infection of the middle ear ([[otitis media]])  
:*Bacterial infection of the middle ear ([[otitis media]])  
*[[Cholesteatoma]], or tumors should be suspected if the onset of facial palsy is gradual.  
:*[[Cholesteatoma]], or tumors should be suspected if the onset of facial palsy is gradual.  
*[[Sarcoidosis]], especially in patients with bilateral facial palsy.  
:*[[Sarcoidosis]], especially in patients with bilateral facial palsy.  
*[[Sjogren's syndrome]] is an unusual cause.
:*[[Sjogren's syndrome]] is an unusual cause.
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 18:38, 26 March 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Many cases are likely due to Herpes Simplex Virus (HSV) reactivation

Infectious Causes

Non-Infectious Causes

  • Several cases of Bell' Palsy were linked to an inactivated intranasal influenza vaccine in Switzerland
  • Genetic predisposition may be likely
  • Ischemia of the facial nerve
  • Tumors and compression of the facial nerve
  • Temporal bone fracture
  • Systemic Lupus Erythematosus (SLE)
  • Sarcoidosis

Lyme Disease

  • Facial nerve palsy is the most common cranial neuropathy associated with Lyme meningitis.
  • Screening for antibodies to B.burgdorferi not recommended among patients with seventh nerve palsy with no additional manifestations of Lyme disease.
  • Findings suggestive of possible Lyme disease include the development of facial palsy in a young patient, heart block, arthritis, vertigo, and hearing loss.

HIV

  • HIV infection rarely causes facial palsy.
  • Onset at the time of sero-conversion when a CSF lymphocytosis is usually present.
  • In the later stages when cellular immunity wanes, the facial palsy is typically due to another infection such as Zoster, chronic demyelinating polyradiculopathy, or meningeal lymphomatosis.

Melkersson-Rosenthal Syndrome

  • Facial paralysis, episodic facial swelling, and a fissured tongue, typically beginning in adolescence, with recurrent episodes of facial palsy.
  • Incomplete forms of this syndrome outnumber those with the classic triad.
  • The cause is unknown, and treatment unproven.

Other Entities

References


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