Appendix cancer differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

appendix cancer must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

appendix cancer must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].

Differentiating appendix cancer from other Diseases

appendix cancer must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

appendix cancer must be differentiated from [differential dx1], [differential dx2], and [differential dx3].

OR

As appendix cancer manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].

Differentiating appendix cancer from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]

On the basis [symptom 1], [symptom 2], and [symptom 3], appendix cancer must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].

Diseases		Clinical manifestations											Para-clinical findings								Gold standard	Additional findings
		Symptoms								Physical examination
													Lab Findings			Imaging				Histopathology
		Abdominal pain	Change in girdle size	Change in bowel habits		Flushing	Palpitation		Other symptoms	Physical exam 1	Physical exam 2	Wheezing	Urinary 5-hydroxyindoleacetic acid (5-HIAA)	Serum Chromogranin A (CgA)	Anemia	CT scan	MRI	Utrasounography	Other imaging modalities
				Diarrhea	Constipation
Appendix cancer	Adenocarcinoma
	Carcinoid tumor
Mucocele
Ovarian tumor
Pseudomyxoma peritonei
Carcinoid syndrome
Appendicitis
	Diseases	Symptom 1	Symptom 2	Symptom 3						Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2		Imaging 3	Histopathology	Gold standard	Additional findings
	Differential Diagnosis 4
	Differential Diagnosis 5
	Differential Diagnosis 6